ISDA: 9XE5

Deposition Date 2025-10-27

Release Date 2026-10-28

Last Version Date 2026-10-28

Entry Detail

PDB ID:

9XE5

Keywords:

TOXIN

Title:

Defensin-like inhibitor of mammalian amylases, magnificamide-2, from the sea anemone Heteractis magnifica

Biological Source:

Source Organism(s):

Heteractis magnifica (Taxon ID: 38281)

Expression System(s):

Escherichia coli

Method Details:

Experimental Method:

SOLUTION NMR

Conformers Calculated:

200

Conformers Submitted:

Selection Criteria:

structures with the least restraint violations

Download Validation Report

Macromolecular Entities

Structures with similar UniProt ID

Structural Superimposition Protein Blast

Polymer Type:polypeptide(L)
Molecule:Alpha-amylase inhibitor magni
Chain IDs:A
Chain Length:44
Number of Molecules:1
Biological Source:Heteractis magnifica

UniProt ID:C0HK71

Ligand Molecules

Primary Citation

Novel beta-defensin-like marine miniprotein magnificamide-2 with a remarkable potency in inhibiting mammalian alpha-amylases.

Popkova, D, Menshov, A, Sintsova, O, Paramonov, A, Kalina, R, Panina, I, Kalinovskii, A, Osmakov, D, Shamatova, M, Dmitrenok, P, Chugunov, A, Kozlov, S, Efremov, R, Shenkarev, Z, Gladkikh, I, Leychenko, E.Show

Int.J.Biol.Macromol. 376 153418 153418 (2026)

PMID: 42419540 DOI: 10.1016/j.ijbiomac.2026.153418

Primary Citation of related structures

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