ISDA: 9XBG

Deposition Date 2025-10-24

Release Date 2026-10-28

Last Version Date 2026-10-28

Entry Detail

PDB ID:

9XBG

Keywords:

CHAPERONE

Title:

Complex of Tetanus Toxin HC Domain with 3A5 Fab Fragment

Biological Source:

Source Organism(s):

Clostridium tetani E88 (Taxon ID: 212717)
Homo sapiens (Taxon ID: 9606)

Expression System(s):

Escherichia coli bl21(de3), Homo sapiens

Method Details:

Experimental Method:

ELECTRON MICROSCOPY

Resolution:

2.75 Å

Aggregation State:

PARTICLE

Reconstruction Method:

SINGLE PARTICLE

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Macromolecular Entities

Structures with similar UniProt ID

Structural Superimposition Protein Blast

Polymer Type:polypeptide(L)
Molecule:Tetanus toxin heavy chain
Gene (Uniprot):tetX
Chain IDs:A
Chain Length:440
Number of Molecules:1
Biological Source:Clostridium tetani E88

UniProt ID:P04958 EC:3.4.24.68

Structural Superimposition Protein Blast

Polymer Type:polypeptide(L)
Molecule:3A5 Fab-H
Chain IDs:B
Chain Length:118
Number of Molecules:1
Biological Source:Homo sapiens

Structural Superimposition Protein Blast

Polymer Type:polypeptide(L)
Molecule:3A5 Fab-K
Chain IDs:C
Chain Length:108
Number of Molecules:1
Biological Source:Homo sapiens

Ligand Molecules

Primary Citation

Potent Neutralization Against Tetanus Neurotoxin In Mice Confered By Antibody Targeting Zinc Metalloproteinase Domain

Zhang, G.Y, Wang, Y.X, Chen, Z.S, Fang, T, Lv, P, Huang, P, Zhu, Z, Cui, Y, Li, J, Li, Z.Y, Dong, Y.Z, Li, J.M, Yu, R, Chi, X.Y, Yu, C.M.Show

To Be Published ? ? ? (?)

Primary Citation of related structures

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