ISDA: 9X74

Deposition Date 2025-10-16

Release Date 2026-08-26

Last Version Date 2026-08-26

Entry Detail

PDB ID:

9X74

Keywords:

MEMBRANE PROTEIN

Title:

Human GPR30 -Gq complex

Biological Source:

Source Organism(s):

Rattus norvegicus (Taxon ID: 10116)
Homo sapiens (Taxon ID: 9606)
Homo sapiens (Taxon ID: 9913)
Mus musculus (Taxon ID: 10090)

Expression System(s):

Spodoptera frugiperda

Method Details:

Experimental Method:

ELECTRON MICROSCOPY

Resolution:

3.15 Å

Aggregation State:

PARTICLE

Reconstruction Method:

SINGLE PARTICLE

Download Validation Report

Macromolecular Entities

Polymer Type:polypeptide(L)
Molecule:Guanine nucleotide-binding pr
Chain IDs:C (auth: A)
Chain Length:258
Number of Molecules:1
Biological Source:Homo sapiens, Bos taurus

Polymer Type:polypeptide(L)
Molecule:Guanine nucleotide-binding pr
Chain IDs:A (auth: B)
Chain Length:374
Number of Molecules:1
Biological Source:Rattus norvegicus

Polymer Type:polypeptide(L)
Molecule:Guanine nucleotide-binding pr
Chain IDs:B (auth: G)
Chain Length:68
Number of Molecules:1
Biological Source:Homo sapiens

Polymer Type:polypeptide(L)
Molecule:G-protein coupled estrogen re
Chain IDs:D (auth: R)
Chain Length:850
Number of Molecules:1
Biological Source:Homo sapiens

Polymer Type:polypeptide(L)
Molecule:scFv16
Chain IDs:E (auth: S)
Chain Length:260
Number of Molecules:1
Biological Source:Mus musculus

Ligand Molecules

Primary Citation

Cryo-EM structure of the bicarbonate receptor GPR30.

Kaneda, S, Jo-Watanabe, A, Akasaka, H, Oshima, H.S, Yokomizo, T, Shihoya, W, Nureki, O.Show

Elife 13 ? ? (2026)

PMID: 42599157 DOI: 10.7554/eLife.99874

Primary Citation of related structures

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