ISDA: 9W8W

Deposition Date 2025-08-08

Release Date 2026-06-24

Last Version Date 2026-06-24

Entry Detail

PDB ID:

9W8W

Keywords:

TRANSCRIPTION

Title:

Structure of backtracked yeast Pol II in complex with a cisplatin-induced inter-strand crosslink lesion at the +2 position.

Biological Source:

Source Organism(s):

synthetic construct (Taxon ID: 32630)
Saccharomyces cerevisiae S288C (Taxon ID: 559292)

Method Details:

Experimental Method:

ELECTRON MICROSCOPY

Resolution:

2.91 Å

Aggregation State:

PARTICLE

Reconstruction Method:

SINGLE PARTICLE

Download Validation Report

Macromolecular Entities

Structures with similar UniProt ID

Structural Superimposition Protein Blast

Polymer Type:polypeptide(L)
Molecule:DNA-directed RNA polymerase I
Gene (Uniprot):RPO21
Chain IDs:L (auth: A)
Chain Length:1733
Number of Molecules:1
Biological Source:Saccharomyces cerevisiae S288C

UniProt ID:P04050 Pfam ID:PF04997, PF00623, PF04983, PF05000, PF04998, PF04992, PF04990, PF05001 EC:2.7.7.6

Structures with similar UniProt ID

Structural Superimposition Protein Blast

Polymer Type:polypeptide(L)
Molecule:DNA-directed RNA polymerase I
Gene (Uniprot):RPB2
Chain IDs:M (auth: B)
Chain Length:1224
Number of Molecules:1
Biological Source:Saccharomyces cerevisiae S288C

UniProt ID:P08518 Pfam ID:PF04563, PF04561, PF04565, PF04566, PF04567, PF00562, PF04560 EC:2.7.7.6

Structures with similar UniProt ID

Structural Superimposition Protein Blast

Polymer Type:polypeptide(L)
Molecule:DNA-directed RNA polymerase I
Gene (Uniprot):RPB3
Chain IDs:D (auth: C)
Chain Length:318
Number of Molecules:1
Biological Source:Saccharomyces cerevisiae S288C

UniProt ID:P16370 Pfam ID:PF01193, PF01000

Structures with similar UniProt ID

Structural Superimposition Protein Blast

Polymer Type:polypeptide(L)
Molecule:DNA-directed RNA polymerase I
Gene (Uniprot):RPB4
Chain IDs:N (auth: D)
Chain Length:221
Number of Molecules:1
Biological Source:Saccharomyces cerevisiae S288C

UniProt ID:P20433 Pfam ID:PF03874

Structures with similar UniProt ID

Structural Superimposition Protein Blast

Polymer Type:polypeptide(L)
Molecule:DNA-directed RNA polymerases
Gene (Uniprot):RPB5
Chain IDs:E
Chain Length:215
Number of Molecules:1
Biological Source:Saccharomyces cerevisiae S288C

UniProt ID:P20434 Pfam ID:PF03871, PF01191

Structures with similar UniProt ID

Structural Superimposition Protein Blast

Polymer Type:polypeptide(L)
Molecule:DNA-directed RNA polymerases
Gene (Uniprot):RPO26
Chain IDs:F
Chain Length:155
Number of Molecules:1
Biological Source:Saccharomyces cerevisiae S288C

UniProt ID:P20435 Pfam ID:PF01192

Structures with similar UniProt ID

Structural Superimposition Protein Blast

Polymer Type:polypeptide(L)
Molecule:DNA-directed RNA polymerase I
Gene (Uniprot):RPB7
Chain IDs:G
Chain Length:171
Number of Molecules:1
Biological Source:Saccharomyces cerevisiae S288C

UniProt ID:P34087 Pfam ID:PF03876, PF00575

Structures with similar UniProt ID

Structural Superimposition Protein Blast

Polymer Type:polypeptide(L)
Molecule:DNA-directed RNA polymerases
Gene (Uniprot):RPB8
Chain IDs:O (auth: H)
Chain Length:146
Number of Molecules:1
Biological Source:Saccharomyces cerevisiae S288C

UniProt ID:P20436 Pfam ID:PF03870

Structures with similar UniProt ID

Structural Superimposition Protein Blast

Polymer Type:polypeptide(L)
Molecule:DNA-directed RNA polymerase I
Gene (Uniprot):RPB9
Chain IDs:H (auth: I)
Chain Length:122
Number of Molecules:1
Biological Source:Saccharomyces cerevisiae S288C

UniProt ID:P27999 Pfam ID:PF02150, PF01096

Structures with similar UniProt ID

Structural Superimposition Protein Blast

Polymer Type:polypeptide(L)
Molecule:DNA-directed RNA polymerases
Gene (Uniprot):RPB10
Chain IDs:I (auth: J)
Chain Length:70
Number of Molecules:1
Biological Source:Saccharomyces cerevisiae S288C

UniProt ID:P22139 Pfam ID:PF01194

Structures with similar UniProt ID

Structural Superimposition Protein Blast

Polymer Type:polypeptide(L)
Molecule:DNA-directed RNA polymerase I
Gene (Uniprot):RPB11
Chain IDs:J (auth: K)
Chain Length:120
Number of Molecules:1
Biological Source:Saccharomyces cerevisiae S288C

UniProt ID:P38902 Pfam ID:PF13656

Structures with similar UniProt ID

Structural Superimposition Protein Blast

Polymer Type:polypeptide(L)
Molecule:DNA-directed RNA polymerases
Gene (Uniprot):RPC10
Chain IDs:K (auth: L)
Chain Length:70
Number of Molecules:1
Biological Source:Saccharomyces cerevisiae S288C

UniProt ID:P40422 Pfam ID:PF03604

Polymer Type:polydeoxyribonucleotide
Molecule:DNA (NTS, non-template strand
Chain IDs:A (auth: N)
Chain Length:10
Number of Molecules:1
Biological Source:synthetic construct

Polymer Type:polyribonucleotide
Molecule:RNA (5'-R(*UP*AP*CP*AP*AP*UP*
Chain IDs:B (auth: P)
Chain Length:21
Number of Molecules:1
Biological Source:synthetic construct

Polymer Type:polydeoxyribonucleotide
Molecule:DNA (TS, template strand)
Chain IDs:C (auth: T)
Chain Length:20
Number of Molecules:1
Biological Source:synthetic construct

Ligand Molecules