ISDA: 9W4T

Deposition Date 2025-08-01

Release Date 2025-11-26

Last Version Date 2026-05-06

Entry Detail

PDB ID:

9W4T

Keywords:

MEMBRANE PROTEIN

Title:

ratTRPV1 bound with antagonist AMG9810

Biological Source:

Source Organism(s):

Escherichia coli K-12 (Taxon ID: 83333)
Rattus norvegicus (Taxon ID: 10116)

Expression System(s):

Homo sapiens

Method Details:

Experimental Method:

ELECTRON MICROSCOPY

Resolution:

2.87 Å

Aggregation State:

PARTICLE

Reconstruction Method:

SINGLE PARTICLE

Download Validation Report

Macromolecular Entities

Protein Blast

Polymer Type:polypeptide(L)
Molecule:Maltose/maltodextrin-binding
Gene (Uniprot):Trpv1, malE
Chain IDs:A, B, C, D
Chain Length:1252
Number of Molecules:4
Biological Source:Escherichia coli K-12, Rattus norvegicus

UniProt ID:P0AEX9,O35433 Pfam ID:PF01547, PF00023, PF00520 EC:7.5.2.1

Ligand Molecules

A1D6W

Primary Citation

Structures of TRPV1 bound by hyperthermia-inducing analgesics

Gao, Y.H, Huang, Y.Z, Li, Z.X, Chen, X.Y, Shao, C.Y, Li, H.W, Liu, B, Yang, F, Chen, M.R, Lu, M.L, Zhu, M.X, Yang, F, Xiao, Y.B, Yu, Y.Show

Cell Rep 45 ? ? (2026)

DOI: 10.1016/j.celrep.2025.116765

Primary Citation of related structures

Feedback Form