9W3M image
Deposition Date 2025-07-29
Release Date 2026-08-05
Last Version Date 2026-08-05
Entry Detail
PDB ID:
9W3M
Keywords:
OXIDOREDUCTASE
Title:
The structures of human dihydroorotate dehydrogenase with inhibitor HL-008
Biological Source:
Source Organism(s):
Homo sapiens (Taxon ID: 9606)
Expression System(s):
Escherichia coli
Method Details:
Experimental Method:
X-RAY DIFFRACTION
Resolution:
1.86 Å
R-Value Free:
0.22
R-Value Work:
0.20
R-Value Observed:
0.20
Space Group:
P 32 2 1
9W3M validation report missing
Macromolecular Entities
Structures with similar UniProt ID
Structural Superimposition Protein Blast
Polymer Type:polypeptide(L)
Molecule:Dihydroorotate dehydrogenase
Gene (Uniprot):DHODH
Chain IDs:A
Chain Length:366
Number of Molecules:1
Biological Source:Homo sapiens
UniProt ID:Q02127 Pfam ID:PF01180 EC:1.3.5.2
Ligand Molecules
A1EUS
FMN
ORO
SO4
Primary Citation
Crystal structure of human DHODH in complex with inhibitor HL-008
To Be Published ? ? ? (?)
Primary Citation of related structures
9W3M
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