ISDA: 9W0P

Deposition Date 2025-07-24

Release Date 2026-04-22

Last Version Date 2026-04-22

Entry Detail

PDB ID:

9W0P

Keywords:

MEMBRANE PROTEIN

Title:

CryoEM structure of T2R14 in complex with chlorhexidine and heterotrimeric G protein complex

Biological Source:

Source Organism(s):

Homo sapiens (Taxon ID: 9606)
Escherichia coli (Taxon ID: 562)

Expression System(s):

Spodoptera frugiperda

Method Details:

Experimental Method:

ELECTRON MICROSCOPY

Resolution:

3.60 Å

Aggregation State:

PARTICLE

Reconstruction Method:

SINGLE PARTICLE

Download Validation Report

Macromolecular Entities

Structures with similar UniProt ID

Protein Blast

Polymer Type:polypeptide(L)
Molecule:Guanine nucleotide-binding pr
Gene (Uniprot):GNAI1
Mutagens:S47N, G202T, G203A, E245A, A326S
Chain IDs:A
Chain Length:354
Number of Molecules:1
Biological Source:Homo sapiens

UniProt ID:P63096 Pfam ID:PF00503

Structures with similar UniProt ID

Protein Blast

Polymer Type:polypeptide(L)
Molecule:Guanine nucleotide-binding pr
Gene (Uniprot):GNB1
Chain IDs:B
Chain Length:351
Number of Molecules:1
Biological Source:Homo sapiens

UniProt ID:P62873 Pfam ID:PF25391

Structures with similar UniProt ID

Protein Blast

Polymer Type:polypeptide(L)
Molecule:Guanine nucleotide-binding pr
Gene (Uniprot):GNG2
Chain IDs:C
Chain Length:71
Number of Molecules:1
Biological Source:Homo sapiens

UniProt ID:P59768 Pfam ID:PF00631

Protein Blast

Polymer Type:polypeptide(L)
Molecule:Soluble cytochrome b562,Taste
Gene (Uniprot):cybC, TAS2R14
Chain IDs:D (auth: R)
Chain Length:483
Number of Molecules:1
Biological Source:Escherichia coli, Homo sapiens

UniProt ID:P0ABE7,Q9NYV8 Pfam ID:PF05296

Ligand Molecules