9VUH image
Deposition Date 2025-07-13
Release Date 2026-07-15
Last Version Date 2026-07-15
Entry Detail
PDB ID:
9VUH
Keywords:
SPLICING
Title:
CDK11B ternary complex bound to AT7519
Biological Source:
Source Organism(s):
Homo sapiens (Taxon ID: 9606)
Expression System(s):
Homo sapiens
Method Details:
Experimental Method:
ELECTRON MICROSCOPY
Resolution:
2.70 Å
Aggregation State:
PARTICLE
Reconstruction Method:
SINGLE PARTICLE
9VUH validation report missing
Macromolecular Entities
Structures with similar UniProt ID
Structural Superimposition Protein Blast
Polymer Type:polypeptide(L)
Molecule:Cyclin-dependent kinase 11B
Gene (Uniprot):CDK11B
Chain IDs:A
Chain Length:332
Number of Molecules:1
Biological Source:Homo sapiens
UniProt ID:P21127 Pfam ID:PF00069 EC:2.7.11.22
Structures with similar UniProt ID
Structural Superimposition Protein Blast
Polymer Type:polypeptide(L)
Molecule:Cyclin-L1
Chain IDs:B
Chain Length:365
Number of Molecules:1
Biological Source:Homo sapiens
UniProt ID:Q9UK58 Pfam ID:PF00134, PF21797
Structures with similar UniProt ID
Structural Superimposition Protein Blast
Polymer Type:polypeptide(L)
Molecule:SAP30-binding protein
Gene (Uniprot):SAP30BP
Chain IDs:C
Chain Length:318
Number of Molecules:1
Biological Source:Homo sapiens
UniProt ID:Q9UHR5 Pfam ID:PF07818
Modified Residue
Compound ID Chain ID Parent Comp ID Details 2D Image
SEP A SER modified residue
TPO A THR modified residue
Ligand Molecules
LZE
Primary Citation
Identification of An Anti-cancer Pre-clinical Candidate as A Potent Inhibitor of RNA Splicing
To Be Published ? ? ? (?)
Primary Citation of related structures
9VUH
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