9VLT image
Deposition Date 2025-06-26
Release Date 2026-04-22
Last Version Date 2026-04-22
Entry Detail
PDB ID:
9VLT
Keywords:
VIRAL PROTEIN/HYDROLASE
Title:
Cryo-EM structure of SARS-CoV-2 XBB.1.5 S trimer in the early fusion intermediate conformation (E-FIC) complexed with ACE2 and 76E1-Fab
Biological Source:
Source Organism(s):
Severe acute respiratory syndrome coronavirus 2 (Taxon ID: 2697049)
Homo sapiens (Taxon ID: 9606)
Expression System(s):
Homo sapiens
Method Details:
Experimental Method:
ELECTRON MICROSCOPY
Resolution:
5.65 Å
Aggregation State:
PARTICLE
Reconstruction Method:
SINGLE PARTICLE
9VLT validation report missing
Macromolecular Entities
Structures with similar UniProt ID
Protein Blast
Polymer Type:polypeptide(L)
Molecule:Spike glycoprotein
Gene (Uniprot):S
Chain IDs:A, E (auth: B), I (auth: C)
Chain Length:1284
Number of Molecules:3
Biological Source:Severe acute respiratory syndrome coronavirus 2
UniProt ID:P0DTC2 Pfam ID:PF16451, PF09408, PF19209, PF01601
Structures with similar UniProt ID
Protein Blast
Polymer Type:polypeptide(L)
Molecule:Angiotensin-converting enzyme
Gene (Uniprot):ACE2
Chain IDs:B (auth: D), F (auth: E), J (auth: F)
Chain Length:631
Number of Molecules:3
Biological Source:Homo sapiens
UniProt ID:Q9BYF1 Pfam ID:PF01401 EC:3.4.15.1
Structures with similar UniProt ID
Protein Blast
Polymer Type:polypeptide(L)
Molecule:heavy chain of 76E1 Fab
Chain IDs:C (auth: G), G (auth: I), K
Chain Length:221
Number of Molecules:3
Biological Source:Homo sapiens
UniProt ID:9VLT
Structures with similar UniProt ID
Protein Blast
Polymer Type:polypeptide(L)
Molecule:light chain of 76E1 Fab
Chain IDs:D (auth: H), H (auth: J), L
Chain Length:216
Number of Molecules:3
Biological Source:Homo sapiens
UniProt ID:9VLT
Ligand Molecules
NAG
Primary Citation
Cryo-EM structure of SARS-CoV-2 XBB.1.5 S trimer in the early fusion intermediate conformation (E-FIC) complexed with ACE2 and 76E1-Fab
To be published ? ? ? (?)
Primary Citation of related structures
9VLS
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