9VLS image
Deposition Date 2025-06-26
Release Date 2026-04-22
Last Version Date 2026-04-22
Entry Detail
PDB ID:
9VLS
Keywords:
VIRAL PROTEIN/IMMUNE SYSTEM
Title:
Cryo-EM structure of SARS-CoV-2 XBB.1.5 S trimer in the early fusion intermediate conformation (E-FIC) complexed with ACE2 and 76E1-Fab (focused refinement of the S2-76E1)
Biological Source:
Source Organism(s):
Severe acute respiratory syndrome coronavirus 2 (Taxon ID: 2697049)
Homo sapiens (Taxon ID: 9606)
Expression System(s):
Homo sapiens
Method Details:
Experimental Method:
ELECTRON MICROSCOPY
Resolution:
4.14 Å
Aggregation State:
PARTICLE
Reconstruction Method:
SINGLE PARTICLE
9VLS validation report missing
Macromolecular Entities
Structures with similar UniProt ID
Protein Blast
Polymer Type:polypeptide(L)
Molecule:Spike glycoprotein
Gene (Uniprot):S
Chain IDs:A, D (auth: B), G (auth: C)
Chain Length:1284
Number of Molecules:3
Biological Source:Severe acute respiratory syndrome coronavirus 2
UniProt ID:P0DTC2 Pfam ID:PF16451, PF09408, PF19209, PF01601
Structures with similar UniProt ID
Protein Blast
Polymer Type:polypeptide(L)
Molecule:heavy chain of 76E1 Fab
Chain IDs:B (auth: G), E (auth: I), H (auth: K)
Chain Length:221
Number of Molecules:3
Biological Source:Homo sapiens
UniProt ID:9VLS
Structures with similar UniProt ID
Protein Blast
Polymer Type:polypeptide(L)
Molecule:light chain of 76E1 Fab
Chain IDs:C (auth: H), F (auth: J), I (auth: L)
Chain Length:216
Number of Molecules:3
Biological Source:Homo sapiens
UniProt ID:9VLS
Ligand Molecules
NAG
Primary Citation
Cryo-EM structure of SARS-CoV-2 XBB.1.5 S trimer in the early fusion intermediate conformation (E-FIC) complexed with ACE2 and 76E1-Fab (focused refinement of the S2-76E1)
To be published ? ? ? (?)
Primary Citation of related structures
9VLS
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