ISDA: 9VH5

Deposition Date 2025-06-16

Release Date 2026-06-24

Last Version Date 2026-06-24

Entry Detail

PDB ID:

9VH5

Keywords:

VIRAL PROTEIN

Title:

Cryo EM structure of hemagglutinin from Puerto Rico/8/1934-New York/55/2004 (H3N2) in complex with a single domain antibody

Biological Source:

Source Organism(s):

Influenza A virus (A/New York/55/2004(H3N2)) (Taxon ID: 518981)
Vicugna pacos (Taxon ID: 30538)

Expression System(s):

Mammalian expression vector flag-mcs-pcdna3.1, Escherichia coli

Method Details:

Experimental Method:

ELECTRON MICROSCOPY

Resolution:

2.70 Å

Aggregation State:

PARTICLE

Reconstruction Method:

SINGLE PARTICLE

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Macromolecular Entities

Structures with similar UniProt ID

Protein Blast

Polymer Type:polypeptide(L)
Molecule:Hemagglutinin
Gene (Uniprot):HA
Chain IDs:A, D, G
Chain Length:321
Number of Molecules:3
Biological Source:Influenza A virus (A/New York/55/2004(H3N2))

UniProt ID:B4UPJ0

Structures with similar UniProt ID

Protein Blast

Polymer Type:polypeptide(L)
Molecule:Hemagglutinin
Gene (Uniprot):HA
Chain IDs:B, E, H
Chain Length:172
Number of Molecules:3
Biological Source:Influenza A virus (A/New York/55/2004(H3N2))

UniProt ID:A0A2P1ADR1

Protein Blast

Polymer Type:polypeptide(L)
Molecule:nanobody
Chain IDs:C, F, I
Chain Length:116
Number of Molecules:3
Biological Source:Vicugna pacos

Ligand Molecules

Primary Citation

Inhalable and broadly neutralizing single-domain antibodies targeting influenza A hemagglutinin

Huang, K.K, Lv, M.W, Kong, Y, Wang, M.K, Ma, X.J, Xu, Q.Y, Zhu, X.Y, Li, W.X, Ying, T.L, Yang, Z.L, Wu, Y.L.Show

To Be Published ? ? ? (?)

Primary Citation of related structures

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