ISDA: 9V90

Deposition Date 2025-05-30

Release Date 2026-04-29

Last Version Date 2026-04-29

Entry Detail

PDB ID:

9V90

Keywords:

SIGNALING PROTEIN

Title:

Crystal structure of the PDZ tandem of syntenin in complex with PDZ2 inhibitor

Biological Source:

Source Organism(s):

Homo sapiens (Taxon ID: 9606)

Expression System(s):

Escherichia coli

Method Details:

Experimental Method:

X-RAY DIFFRACTION

Resolution:

1.40 Å

R-Value Free:

0.22

R-Value Work:

0.18

R-Value Observed:

0.18

Space Group:

P 1 21 1

Download Validation Report

Macromolecular Entities

Structures with similar UniProt ID

Protein Blast

Polymer Type:polypeptide(L)
Molecule:Syntenin-1
Gene (Uniprot):SDCBP
Chain IDs:A, B
Chain Length:163
Number of Molecules:2
Biological Source:Homo sapiens

UniProt ID:O00560

Ligand Molecules

ACT

LKV

Primary Citation

Intrinsically Dominant Conformational Diversity in PDZ1 within the Tandem PDZ1-PDZ2 of Human Syntenin-1 Underlined by Crystal Structures.

Ando, N, Hanazono, Y, Sakuma, K, Numoto, N, Tenno, T, Oshima, A, Ito, N, Hiroaki, H.Show

To Be Published ? ? ? (?)

Primary Citation of related structures

Feedback Form