ISDA: 9UWV

Deposition Date 2025-05-12

Release Date 2026-05-27

Last Version Date 2026-05-27

Entry Detail

PDB ID:

9UWV

Keywords:

MEMBRANE PROTEIN

Title:

SalA bound Kappa Opioid Receptor in complex with Gi

Biological Source:

Source Organism(s):

Homo sapiens (Taxon ID: 9606)
Rattus norvegicus (Taxon ID: 10116)
Bos taurus (Taxon ID: 9913)
synthetic construct (Taxon ID: 32630)

Expression System(s):

Spodoptera frugiperda

Method Details:

Experimental Method:

ELECTRON MICROSCOPY

Resolution:

3.30 Å

Aggregation State:

PARTICLE

Reconstruction Method:

SINGLE PARTICLE

Download Validation Report

Macromolecular Entities

Structures with similar UniProt ID

Protein Blast

Polymer Type:polypeptide(L)
Molecule:Guanine nucleotide-binding pr
Gene (Uniprot):Gnb1
Chain IDs:B
Chain Length:353
Number of Molecules:1
Biological Source:Rattus norvegicus

UniProt ID:P54311 Pfam ID:PF25391

Structures with similar UniProt ID

Protein Blast

Polymer Type:polypeptide(L)
Molecule:Guanine nucleotide-binding pr
Gene (Uniprot):GNG2
Chain IDs:C
Chain Length:71
Number of Molecules:1
Biological Source:Bos taurus

UniProt ID:P63212 Pfam ID:PF00631

Structures with similar UniProt ID

Protein Blast

Polymer Type:polypeptide(L)
Molecule:Guanine nucleotide-binding pr
Gene (Uniprot):GNAI1
Chain IDs:A (auth: D)
Chain Length:354
Number of Molecules:1
Biological Source:Homo sapiens

UniProt ID:P63096 Pfam ID:PF00503 EC:3.6.5.-

Protein Blast

Polymer Type:polypeptide(L)
Molecule:scFv16
Chain IDs:D (auth: E)
Chain Length:266
Number of Molecules:1
Biological Source:synthetic construct

Structures with similar UniProt ID

Protein Blast

Polymer Type:polypeptide(L)
Molecule:Kappa-type opioid receptor
Gene (Uniprot):OPRK1
Chain IDs:E (auth: R)
Chain Length:397
Number of Molecules:1
Biological Source:Homo sapiens

UniProt ID:P41145 Pfam ID:PF00001

Ligand Molecules

A1EQK

Primary Citation

Structural and pharmacological profiling of kappa-opioid receptor homodimerizatio

Wang, Y, Zhuang, Y, Xu, H.E.Show

To Be Published ? ? ? (?)

Primary Citation of related structures

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