9TV9 image
Deposition Date 2026-01-12
Release Date 2026-06-10
Last Version Date 2026-06-10
Entry Detail
PDB ID:
9TV9
Keywords:
DNA BINDING PROTEIN
Title:
Designed variant of HigB2-HigA2 tetrameter in the bent conformation
Biological Source:
Source Organism(s):
Vibrio cholerae (Taxon ID: 666)
Expression System(s):
Escherichia coli 'bl21-gold(de3)plyss ag'
Method Details:
Experimental Method:
X-RAY DIFFRACTION
Resolution:
2.00 Å
R-Value Free:
0.24
R-Value Work:
0.21
R-Value Observed:
0.21
Space Group:
C 1 2 1
9TV9 validation report missing
Macromolecular Entities
Structures with similar UniProt ID
Protein Blast
Polymer Type:polypeptide(L)
Molecule:Antitoxin HigA-2
Gene (Uniprot):higA-2
Mutagens:E50D Q51S F52H M54L V58Q R61T S99A H100L
Chain IDs:A, B
Chain Length:103
Number of Molecules:2
Biological Source:Vibrio cholerae
UniProt ID:Q9KMA5 Pfam ID:PF15731
Structures with similar UniProt ID
Protein Blast
Polymer Type:polypeptide(L)
Molecule:Toxin HigB-2
Gene (Uniprot):higB-2
Mutagens:R25K A29H E30K M32A
Chain IDs:C, D
Chain Length:129
Number of Molecules:2
Biological Source:Vibrio cholerae
UniProt ID:Q9KMA6 Pfam ID:PF06296
Ligand Molecules
ACE
EDO
PEG
SO4
Primary Citation
A fuzzy-to-ordered switch in the binding mode of the disordered regulator HigA2 mediates a functional ratio-sensing gene circuit
To Be Published ? ? ? (?)
Primary Citation of related structures
9TV9
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