9TML image
Deposition Date 2025-12-15
Release Date 2026-11-04
Last Version Date 2026-11-04
Entry Detail
PDB ID:
9TML
Keywords:
IMMUNE SYSTEM
Title:
Structure of TCR-B targeting GPC3 [FLAELAYDL] peptide bound to HLA-A*02:01
Biological Source:
Source Organism(s):
Homo sapiens (Taxon ID: 9606)
Expression System(s):
Escherichia coli, Cricetulus griseus, Synthetic construct
Method Details:
Experimental Method:
X-RAY DIFFRACTION
Resolution:
1.95 Å
R-Value Free:
0.29
R-Value Work:
0.26
R-Value Observed:
0.26
Space Group:
C 1 2 1
9TML validation report missing
Macromolecular Entities
Structures with similar UniProt ID
Structural Superimposition Protein Blast
Polymer Type:polypeptide(L)
Molecule:MHC class I antigen
Gene (Uniprot):HLA-A
Chain IDs:A
Chain Length:280
Number of Molecules:1
Biological Source:Homo sapiens
UniProt ID:A5I8L1
Structures with similar UniProt ID
Structural Superimposition Protein Blast
Polymer Type:polypeptide(L)
Molecule:Beta-2-microglobulin
Gene (Uniprot):B2M
Chain IDs:B
Chain Length:101
Number of Molecules:1
Biological Source:Homo sapiens
UniProt ID:P61769
Structural Superimposition Protein Blast
Polymer Type:polypeptide(L)
Molecule:TCR-B alpha chain
Chain IDs:C
Chain Length:213
Number of Molecules:1
Biological Source:Homo sapiens
Structural Superimposition Protein Blast
Polymer Type:polypeptide(L)
Molecule:TCR-B beta chain
Chain IDs:D
Chain Length:244
Number of Molecules:1
Biological Source:Homo sapiens
Structures with similar UniProt ID
Structural Superimposition Protein Blast
Polymer Type:polypeptide(L)
Molecule:Glypican-3 beta subunit
Gene (Uniprot):GPC3
Chain IDs:E (auth: P)
Chain Length:9
Number of Molecules:1
Biological Source:Homo sapiens
UniProt ID:P51654
Ligand Molecules
GOL
MES
NA
NAG
Primary Citation
Structure-function profiling identifies determinants of TCR-T cell therapeutic efficacy
To Be Published ? ? ? (?)
Primary Citation of related structures
9TML
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