9TJV image
Deposition Date 2025-12-08
Release Date 2026-08-05
Last Version Date 2026-08-05
Entry Detail
PDB ID:
9TJV
Keywords:
RNA BINDING PROTEIN
Title:
Ternary complex of E. coli leucyl-tRNA synthetase mutant W177A, tRNA(leu) and the leucyl adenylate analog LeuAMS in the aminoacyl transfer state
Biological Source:
Source Organism(s):
Escherichia coli (Taxon ID: 562)
Expression System(s):
Escherichia coli, In vitro transcription vector pt7-fluc(deltai)
Method Details:
Experimental Method:
X-RAY DIFFRACTION
Resolution:
2.28 Å
R-Value Free:
0.22
R-Value Work:
0.19
R-Value Observed:
0.19
Space Group:
C 1 2 1
9TJV validation report missing
Macromolecular Entities
Structures with similar UniProt ID
Structural Superimposition Protein Blast
Polymer Type:polypeptide(L)
Molecule:Leucine--tRNA ligase
Gene (Uniprot):leuS
Mutagens:W177A
Chain IDs:A, C
Chain Length:880
Number of Molecules:2
Biological Source:Escherichia coli
UniProt ID:C4ZWC9 EC:6.1.1.4
Polymer Type:polyribonucleotide
Molecule:tRNA(leu)
Chain IDs:B, D
Chain Length:87
Number of Molecules:2
Biological Source:Escherichia coli
Ligand Molecules
LSS
MG
Primary Citation
The Zn Domain Acts as a Dynamic Switch Coordinating Multiple-Step Aminoacylation in Bacterial Leucyl-tRNA Synthetase
Nucleic Acids Res. ? ? ? (2026)
DOI: 10.1093/nar/gkag786
Primary Citation of related structures
9TJV
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