9TGM image
Deposition Date 2025-12-02
Release Date 2026-08-26
Last Version Date 2026-08-26
Entry Detail
PDB ID:
9TGM
Keywords:
Title:
Cryo-EM structure of MCM2-7 DH bound to Sld3-Sld7
Biological Source:
Source Organism(s):
Expression System(s):
Method Details:
Experimental Method:
Resolution:
3.60 Å
Aggregation State:
PARTICLE
Reconstruction Method:
SINGLE PARTICLE
Macromolecular Entities
Polymer Type:polypeptide(L)
Molecule:DNA replication licensing fac
Chain IDs:A (auth: 2), H (auth: B)
Chain Length:868
Number of Molecules:2
Biological Source:Saccharomyces cerevisiae
Polymer Type:polypeptide(L)
Molecule:DNA replication licensing fac
Chain IDs:B (auth: 3), I (auth: C)
Chain Length:971
Number of Molecules:2
Biological Source:Saccharomyces cerevisiae
Polymer Type:polypeptide(L)
Molecule:DNA replication licensing fac
Chain IDs:C (auth: 4), J (auth: D)
Chain Length:933
Number of Molecules:2
Biological Source:Saccharomyces cerevisiae
Polymer Type:polypeptide(L)
Molecule:Minichromosome maintenance pr
Chain IDs:D (auth: 5), K (auth: E)
Chain Length:775
Number of Molecules:2
Biological Source:Saccharomyces cerevisiae
Polymer Type:polypeptide(L)
Molecule:DNA replication licensing fac
Chain IDs:E (auth: 6), L (auth: F)
Chain Length:1017
Number of Molecules:2
Biological Source:Saccharomyces cerevisiae
Polymer Type:polypeptide(L)
Molecule:DNA replication licensing fac
Chain IDs:F (auth: 7), M (auth: G)
Chain Length:845
Number of Molecules:2
Biological Source:Saccharomyces cerevisiae
Polymer Type:polypeptide(L)
Molecule:DNA replication regulator SLD
Chain IDs:G (auth: 8), N (auth: X)
Chain Length:668
Number of Molecules:2
Biological Source:Saccharomyces cerevisiae
Polymer Type:polypeptide(L)
Molecule:Mitochondrial morphogenesis p
Chain IDs:O (auth: Y)
Chain Length:257
Number of Molecules:1
Biological Source:Saccharomyces cerevisiae
Primary Citation
Structural insights into Sld3-Sld7-dependent Cdc45 loading during replication initiation
Nat Commun ? ? ? (2026)
DOI: 10.1038/s41467-026-76309-6
Primary Citation of related structures
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