ISDA: 9TCC

Deposition Date 2025-11-21

Release Date 2026-07-22

Last Version Date 2026-07-22

Entry Detail

PDB ID:

9TCC

Keywords:

VIRAL PROTEIN

Title:

African Horse Sickness Virus serotype 4 VP2 homotrimer

Biological Source:

Source Organism(s):

African horse sickness virus 4 (Taxon ID: 36421)

Expression System(s):

Mesocricetus auratus

Method Details:

Experimental Method:

ELECTRON MICROSCOPY

Resolution:

3.11 Å

Aggregation State:

PARTICLE

Reconstruction Method:

SINGLE PARTICLE

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Macromolecular Entities

Structures with similar UniProt ID

Structural Superimposition Protein Blast

Polymer Type:polypeptide(L)
Molecule:Outer capsid protein VP2
Chain IDs:A, B, C
Chain Length:1073
Number of Molecules:3
Biological Source:African horse sickness virus 4

UniProt ID:A0A0B5GT51 Pfam ID:PF00898

Ligand Molecules

Primary Citation

Cryo-EM structure of African horse sickness virus VP2 receptor-binding protein enables nanoparticle vaccine design.

Martinez-Castillo, A, Aebischer, A, Toneatti, P, Fu, L, Vitour, D, Sailleau, C, Hoffmann, B, Franzke, K, Eschbaumer, M, Weber, S, Calvo Pinilla, E, Ortego, J, Gil-Carton, D, Breard, E, Zientara, S, Kortekaas, J, Beer, M, Abrescia, N.G.Show

Nat Commun ? ? ? (2026)

PMID: 42401561 DOI: 10.1038/s41467-026-75067-9

Primary Citation of related structures

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