ISDA: 9TC9

Deposition Date 2025-11-20

Release Date 2026-11-04

Last Version Date 2026-11-04

Entry Detail

PDB ID:

9TC9

Keywords:

MEMBRANE PROTEIN

Title:

Active-state structure of the GPR55-N171Q mutant in complex with G13 and BI-6229

Biological Source:

Source Organism(s):

Homo sapiens (Taxon ID: 9606)
Synthetic construct (Taxon ID: 32630)
Aequorea victoria (Taxon ID: 6100)

Expression System(s):

Trichoplusia ni

Method Details:

Experimental Method:

ELECTRON MICROSCOPY

Resolution:

2.88 Å

Aggregation State:

PARTICLE

Reconstruction Method:

SINGLE PARTICLE

Download Validation Report

Macromolecular Entities

Structural Superimposition Protein Blast

Polymer Type:polypeptide(L)
Molecule:Guanine nucleotide-binding pr
Gene (Uniprot):GNAI2, GNA13
Chain IDs:A
Chain Length:230
Number of Molecules:1
Biological Source:Homo sapiens

UniProt ID:P04899,Q14344

Structures with similar UniProt ID

Structural Superimposition Protein Blast

Polymer Type:polypeptide(L)
Molecule:Guanine nucleotide-binding pr
Gene (Uniprot):GNB1
Chain IDs:B
Chain Length:358
Number of Molecules:1
Biological Source:Homo sapiens

UniProt ID:P62873

Structural Superimposition Protein Blast

Polymer Type:polypeptide(L)
Molecule:ScFv16
Chain IDs:C (auth: F)
Chain Length:304
Number of Molecules:1
Biological Source:Synthetic construct

Structures with similar UniProt ID

Structural Superimposition Protein Blast

Polymer Type:polypeptide(L)
Molecule:Guanine nucleotide-binding pr
Gene (Uniprot):GNG2
Chain IDs:D (auth: G)
Chain Length:80
Number of Molecules:1
Biological Source:Homo sapiens

UniProt ID:P59768

Structural Superimposition Protein Blast

Polymer Type:polypeptide(L)
Molecule:Green fluorescent protein,G-p
Gene (Uniprot):GFP, GPR55
Chain IDs:E (auth: R)
Chain Length:650
Number of Molecules:1
Biological Source:Aequorea victoria, Homo sapiens

UniProt ID:P42212,Q9Y2T6

Ligand Molecules