ISDA: 9TC8

Deposition Date 2025-11-20

Release Date 2026-11-04

Last Version Date 2026-11-04

Entry Detail

PDB ID:

9TC8

Keywords:

MEMBRANE PROTEIN

Title:

Inactive-state structure of GPR55 in complex with BI-8310

Biological Source:

Source Organism(s):

Aequorea victoria (Taxon ID: 6100)
Homo sapiens (Taxon ID: 9606)
Escherichia coli (Taxon ID: 562)
Synthetic construct (Taxon ID: 32630)

Expression System(s):

Trichoplusia ni, Cricetulus griseus, Escherichia coli

Method Details:

Experimental Method:

ELECTRON MICROSCOPY

Resolution:

2.76 Å

Aggregation State:

PARTICLE

Reconstruction Method:

SINGLE PARTICLE

Download Validation Report

Macromolecular Entities

Structural Superimposition Protein Blast

Polymer Type:polypeptide(L)
Molecule:Green fluorescent protein,G-p
Gene (Uniprot):cybC, GFP, GPR55
Chain IDs:A
Chain Length:741
Number of Molecules:1
Biological Source:Aequorea victoria, Homo sapiens, Escherichia coli

UniProt ID:P42212,Q9Y2T6,P0ABE7

Structural Superimposition Protein Blast

Polymer Type:polypeptide(L)
Molecule:anti-bRIL fab heavy-chain
Chain IDs:B (auth: H)
Chain Length:245
Number of Molecules:1
Biological Source:Synthetic construct

Structural Superimposition Protein Blast

Polymer Type:polypeptide(L)
Molecule:anti-bRIL fab light-chain
Chain IDs:C (auth: L)
Chain Length:232
Number of Molecules:1
Biological Source:Synthetic construct

Structural Superimposition Protein Blast

Polymer Type:polypeptide(L)
Molecule:Fab-Nb
Chain IDs:D (auth: N)
Chain Length:162
Number of Molecules:1
Biological Source:Synthetic construct

Ligand Molecules