9T0A image
Deposition Date 2025-10-16
Release Date 2026-03-11
Last Version Date 2026-04-08
Entry Detail
PDB ID:
9T0A
Keywords:
HYDROLASE
Title:
X-ray structure of the complex between the catalytic domain of CDC25B C473S and 3-O-methylfluorescein phosphate (3-OMFP)
Biological Source:
Source Organism(s):
Homo sapiens (Taxon ID: 9606)
Expression System(s):
Escherichia coli bl21(de3)
Method Details:
Experimental Method:
X-RAY DIFFRACTION
Resolution:
2.04 Å
R-Value Free:
0.21
R-Value Work:
0.19
R-Value Observed:
0.19
Space Group:
P 21 21 21
9T0A validation report missing
Macromolecular Entities
Structures with similar UniProt ID
Protein Blast
Polymer Type:polypeptide(L)
Molecule:M-phase inducer phosphatase 2
Gene (Uniprot):CDC25B
Mutagens:C473S
Chain IDs:A
Chain Length:197
Number of Molecules:1
Biological Source:Homo sapiens
UniProt ID:P30305 Pfam ID:PF00581 EC:3.1.3.48
Ligand Molecules
A1JSP
A1JSQ
CL
Primary Citation
The Binding of 3-O-Methylfluorescein Phosphate to the Catalytic Domain of the Human CDC25B Phosphatase: A Structural Investigation.
Chembiochem 27 e202600010 e202600010 (2026)
PMID: 41906666 DOI: 10.1002/cbic.202600010
Primary Citation of related structures
9T09
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