ISDA: 9T09

Deposition Date 2025-10-16

Release Date 2026-03-11

Last Version Date 2026-04-08

Entry Detail

PDB ID:

9T09

Keywords:

HYDROLASE

Title:

X-ray structure of the catalytic domain of CDC25B C473S at 1.34 angstrom resolution

Biological Source:

Source Organism(s):

Homo sapiens (Taxon ID: 9606)

Expression System(s):

Escherichia coli bl21(de3)

Method Details:

Experimental Method:

X-RAY DIFFRACTION

Resolution:

1.34 Å

R-Value Free:

0.17

R-Value Work:

0.15

R-Value Observed:

0.15

Space Group:

P 21 21 21

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Macromolecular Entities

Structures with similar UniProt ID

Protein Blast

Polymer Type:polypeptide(L)
Molecule:M-phase inducer phosphatase 2
Gene (Uniprot):CDC25B
Mutagens:C473S
Chain IDs:A
Chain Length:197
Number of Molecules:1
Biological Source:Homo sapiens

UniProt ID:P30305 Pfam ID:PF00581 EC:3.1.3.48

Ligand Molecules

GOL

SO4

Primary Citation

The Binding of 3-O-Methylfluorescein Phosphate to the Catalytic Domain of the Human CDC25B Phosphatase: A Structural Investigation.

Troisi, R, Rullo, R, Napolitano, V, Popowicz, G.M, De Vendittis, E, Sica, F.Show

Chembiochem 27 e202600010 e202600010 (2026)

PMID: 41906666 DOI: 10.1002/cbic.202600010

Primary Citation of related structures

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