ISDA: 9SYM

Deposition Date 2025-10-13

Release Date 2026-10-28

Last Version Date 2026-10-28

Entry Detail

PDB ID:

9SYM

Keywords:

TRANSFERASE

Title:

Structure of human DNMT2 with bound competitive inhibitor

Biological Source:

Source Organism(s):

Homo sapiens (Taxon ID: 9606)

Expression System(s):

Escherichia coli bl21(de3)

Method Details:

Experimental Method:

X-RAY DIFFRACTION

Resolution:

2.00 Å

R-Value Free:

0.21

R-Value Work:

0.17

R-Value Observed:

0.17

Space Group:

I 41

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Macromolecular Entities

Structures with similar UniProt ID

Structural Superimposition Protein Blast

Polymer Type:polypeptide(L)
Molecule:tRNA (cytosine(38)-C(5))-meth
Gene (Uniprot):TRDMT1
Chain IDs:A
Chain Length:348
Number of Molecules:1
Biological Source:Homo sapiens

UniProt ID:O14717 EC:2.1.1.202

Modified Residue

Compound ID	Chain ID	Parent Comp ID	Details	2D Image
CME	A	CYS	modified residue

Ligand Molecules

A1JR0

EDO

GLY

GOL

SO4

Primary Citation

Structure of human DNMT2 with bound competitive inhibitor

Schwan, M, Kopp, J, Sinning, I.Show

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