9SW8 image
Deposition Date 2025-10-04
Release Date 2026-10-14
Last Version Date 2026-10-14
Entry Detail
PDB ID:
9SW8
Keywords:
LYASE
Title:
Crystal structure of human carbonic anhydrase II in complex with 4-(4-((4-ethoxy-3-(1-methyl-7-oxo-3-propyl-6,7-dihydro-1H-pyrazolo[4,3-d]pyrimidin-5-yl)phenyl)sulfonyl)-1,4-diazepan-1-yl)-3-fluorobenzenesulfonamide
Biological Source:
Source Organism(s):
Homo sapiens (Taxon ID: 9606)
Expression System(s):
Escherichia coli
Method Details:
Experimental Method:
X-RAY DIFFRACTION
Resolution:
1.11 Å
R-Value Free:
0.17
R-Value Work:
0.14
Space Group:
P 1 21 1
9SW8 validation report missing
Macromolecular Entities
Structures with similar UniProt ID
Structural Superimposition Protein Blast
Polymer Type:polypeptide(L)
Molecule:Carbonic anhydrase 2
Gene (Uniprot):CA2
Chain IDs:A (auth: AAA)
Chain Length:260
Number of Molecules:1
Biological Source:Homo sapiens
UniProt ID:P00918 EC:4.2.1.1
Ligand Molecules
A1JQ3
EDO
GOL
ZN
Primary Citation
Crystal structure of human carbonic anhydrase II in complex with 4-(4-((4-ethoxy-3-(1-methyl-7-oxo-3-propyl-6,7-dihydro-1H-pyrazolo[4,3-d]pyrimidin-5-yl)phenyl)sulfonyl)-1,4-diazepan-1-yl)-3-fluorobenzenesulfonamide
To Be Published ? ? ? (?)
Primary Citation of related structures
9SW8
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