ISDA: 9SVL

Deposition Date 2025-10-03

Release Date 2026-10-14

Last Version Date 2026-10-14

Entry Detail

PDB ID:

9SVL

Keywords:

LYASE

Title:

Crystal structure of human carbonic anhydrase II in complex with 4-ethoxy-3-(1-methyl-7-oxo-3-propyl-6,7-dihydro-1H-pyrazolo[4,3-d]pyrimidin-5-yl)benzenesulfonamide

Biological Source:

Source Organism(s):

Homo sapiens (Taxon ID: 9606)

Expression System(s):

Escherichia coli

Method Details:

Experimental Method:

X-RAY DIFFRACTION

Resolution:

1.51 Å

R-Value Free:

0.22

R-Value Work:

0.18

Space Group:

P 1 21 1

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Macromolecular Entities

Structures with similar UniProt ID

Structural Superimposition Protein Blast

Polymer Type:polypeptide(L)
Molecule:Carbonic anhydrase 2
Gene (Uniprot):CA2
Chain IDs:A (auth: AAA)
Chain Length:260
Number of Molecules:1
Biological Source:Homo sapiens

UniProt ID:P00918 EC:4.2.1.1

Ligand Molecules

A1JQ8

EDO

GOL

Primary Citation

Crystal structure of human carbonic anhydrase II in complex with 4-ethoxy-3-(1-methyl-7-oxo-3-propyl-6,7-dihydro-1H-pyrazolo[4,3-d]pyrimidin-5-yl)benzenesulfonamide

Angeli, A, Ferraroni, M.Show

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