ISDA: 9SRU

Deposition Date 2025-09-25

Release Date 2026-07-22

Last Version Date 2026-07-22

Entry Detail

PDB ID:

9SRU

Keywords:

DNA BINDING PROTEIN

Title:

Cryo-EM structure of Mlc in complex with ptsG operator DNA

Biological Source:

Source Organism(s):

Escherichia coli (Taxon ID: 562)

Expression System(s):

Escherichia coli

Method Details:

Experimental Method:

ELECTRON MICROSCOPY

Resolution:

2.47 Å

Aggregation State:

PARTICLE

Reconstruction Method:

SINGLE PARTICLE

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Macromolecular Entities

Structures with similar UniProt ID

Structural Superimposition Protein Blast

Polymer Type:polypeptide(L)
Molecule:DNA-binding transcriptional r
Gene (Uniprot):mlc
Chain IDs:A, B, C, D
Chain Length:455
Number of Molecules:4
Biological Source:Escherichia coli

UniProt ID:P50456 Pfam ID:PF00480

Polymer Type:polydeoxyribonucleotide
Molecule:DNA (27-MER)
Chain IDs:E, H
Chain Length:29
Number of Molecules:2
Biological Source:Escherichia coli

Polymer Type:polydeoxyribonucleotide
Molecule:DNA (27-MER)
Chain IDs:F, G
Chain Length:29
Number of Molecules:2
Biological Source:Escherichia coli

Ligand Molecules

Primary Citation

Structural basis of Mlc-mediated transcriptional regulation of carbohydrate metabolism.

Roth, P, Fender, I, Jeckelmann, J.M, Ucurum, Z, Lemmin, T, Fotiadis, D.Show

Nat Commun ? ? ? (2026)

PMID: 42436118 DOI: 10.1038/s41467-026-75270-8

Primary Citation of related structures

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