ISDA: 9SMR

Deposition Date 2025-09-09

Release Date 2026-07-08

Last Version Date 2026-07-08

Entry Detail

PDB ID:

9SMR

Keywords:

METAL BINDING PROTEIN

Title:

Structure of apo BRCA1-A complex in presence of K63-oligoUbATA

Biological Source:

Source Organism(s):

Homo sapiens (Taxon ID: 9606)

Expression System(s):

Spodoptera frugiperda

Method Details:

Experimental Method:

ELECTRON MICROSCOPY

Resolution:

3.25 Å

Aggregation State:

PARTICLE

Reconstruction Method:

SINGLE PARTICLE

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Macromolecular Entities

Structures with similar UniProt ID

Protein Blast

Polymer Type:polypeptide(L)
Molecule:BRCA1-A complex subunit Abrax
Gene (Uniprot):ABRAXAS1
Chain IDs:A, F
Chain Length:409
Number of Molecules:2
Biological Source:Homo sapiens

UniProt ID:Q6UWZ7 Pfam ID:PF21125

Structures with similar UniProt ID

Protein Blast

Polymer Type:polypeptide(L)
Molecule:Lys-63-specific deubiquitinas
Gene (Uniprot):BRCC3
Chain IDs:B, G
Chain Length:316
Number of Molecules:2
Biological Source:Homo sapiens

UniProt ID:P46736 Pfam ID:PF01398, PF18110 EC:3.4.19.-

Structures with similar UniProt ID

Protein Blast

Polymer Type:polypeptide(L)
Molecule:BRISC and BRCA1-A complex mem
Gene (Uniprot):BABAM2
Chain IDs:C, H
Chain Length:383
Number of Molecules:2
Biological Source:Homo sapiens

UniProt ID:Q9NXR7 Pfam ID:PF06113

Structures with similar UniProt ID

Protein Blast

Polymer Type:polypeptide(L)
Molecule:BRISC and BRCA1-A complex mem
Gene (Uniprot):BABAM1
Chain IDs:D, J (auth: I)
Chain Length:349
Number of Molecules:2
Biological Source:Homo sapiens

UniProt ID:Q9NWV8

Structures with similar UniProt ID

Protein Blast

Polymer Type:polypeptide(L)
Molecule:BRCA1-A complex subunit RAP80
Gene (Uniprot):UIMC1
Chain IDs:E, I (auth: J)
Chain Length:171
Number of Molecules:2
Biological Source:Homo sapiens

UniProt ID:Q96RL1

Ligand Molecules

Primary Citation

A ubiquitin chain-feeding mechanism for BRCA1-A

Murachelli, A.G, El Oualid, F, Sixma, T.K.Show

Biorxiv ? ? ? (2026)

DOI: 10.64898/2026.06.05.730370

Primary Citation of related structures

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