9SMR image
Deposition Date 2025-09-09
Release Date 2026-07-08
Last Version Date 2026-08-19
Entry Detail
PDB ID:
9SMR
Keywords:
METAL BINDING PROTEIN
Title:
Structure of apo BRCA1-A complex in presence of K63-oligoUbATA
Biological Source:
Source Organism(s):
Homo sapiens (Taxon ID: 9606)
Expression System(s):
Spodoptera frugiperda
Method Details:
Experimental Method:
ELECTRON MICROSCOPY
Resolution:
3.25 Å
Aggregation State:
PARTICLE
Reconstruction Method:
SINGLE PARTICLE
9SMR validation report missing
Macromolecular Entities
Polymer Type:polypeptide(L)
Molecule:BRCA1-A complex subunit Abrax
Chain IDs:A, F
Chain Length:409
Number of Molecules:2
Biological Source:Homo sapiens
Polymer Type:polypeptide(L)
Molecule:Lys-63-specific deubiquitinas
Chain IDs:B, G
Chain Length:316
Number of Molecules:2
Biological Source:Homo sapiens
Polymer Type:polypeptide(L)
Molecule:BRISC and BRCA1-A complex mem
Chain IDs:C, H
Chain Length:383
Number of Molecules:2
Biological Source:Homo sapiens
Polymer Type:polypeptide(L)
Molecule:BRISC and BRCA1-A complex mem
Chain IDs:D, J (auth: I)
Chain Length:349
Number of Molecules:2
Biological Source:Homo sapiens
Polymer Type:polypeptide(L)
Molecule:BRCA1-A complex subunit RAP80
Chain IDs:E, I (auth: J)
Chain Length:171
Number of Molecules:2
Biological Source:Homo sapiens
Ligand Molecules
ZN
Primary Citation
A ubiquitin chain-feeding mechanism for BRCA1-A.
Nat Commun 17 ? ? (2026)
PMID: 42581048 DOI: 10.1038/s41467-026-75797-w
Primary Citation of related structures
9SMN
9SMP
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