9SMN image
Deposition Date 2025-09-08
Release Date 2026-06-17
Last Version Date 2026-08-19
Entry Detail
PDB ID:
9SMN
Keywords:
METAL BINDING PROTEIN
Title:
BRCA1-A complex bound to K63-polyUbATA - open form StateC StateP
Biological Source:
Source Organism(s):
Homo sapiens (Taxon ID: 9606)
Expression System(s):
Spodoptera frugiperda
Method Details:
Experimental Method:
ELECTRON MICROSCOPY
Resolution:
3.20 Å
Aggregation State:
PARTICLE
Reconstruction Method:
SINGLE PARTICLE
9SMN validation report missing
Macromolecular Entities
Polymer Type:polypeptide(L)
Molecule:BRCA1-A complex subunit Abrax
Chain IDs:A, F
Chain Length:409
Number of Molecules:2
Biological Source:Homo sapiens
Polymer Type:polypeptide(L)
Molecule:Lys-63-specific deubiquitinas
Chain IDs:B, G
Chain Length:316
Number of Molecules:2
Biological Source:Homo sapiens
Polymer Type:polypeptide(L)
Molecule:BRISC and BRCA1-A complex mem
Chain IDs:C, H
Chain Length:383
Number of Molecules:2
Biological Source:Homo sapiens
Polymer Type:polypeptide(L)
Molecule:BRISC and BRCA1-A complex mem
Chain IDs:D, I
Chain Length:349
Number of Molecules:2
Biological Source:Homo sapiens
Polymer Type:polypeptide(L)
Molecule:BRCA1-A complex subunit RAP80
Chain IDs:E, J
Chain Length:171
Number of Molecules:2
Biological Source:Homo sapiens
Polymer Type:polypeptide(L)
Molecule:Polyubiquitin-C
Chain IDs:K, M
Chain Length:76
Number of Molecules:2
Biological Source:Homo sapiens
Polymer Type:polypeptide(L)
Molecule:Polyubiquitin-C
Chain IDs:L, N
Chain Length:76
Number of Molecules:2
Biological Source:Homo sapiens
Polymer Type:polypeptide(L)
Molecule:Ubiquitin
Chain IDs:O (auth: S), P (auth: T), Q (auth: U), R (auth: V)
Chain Length:76
Number of Molecules:4
Biological Source:Homo sapiens
Ligand Molecules
ZN
Primary Citation
A ubiquitin chain-feeding mechanism for BRCA1-A.
Nat Commun 17 ? ? (2026)
PMID: 42581048 DOI: 10.1038/s41467-026-75797-w
Primary Citation of related structures
9SMN
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