ISDA: 9SCX

Deposition Date 2025-08-12

Release Date 2026-03-18

Last Version Date 2026-03-18

Entry Detail

PDB ID:

9SCX

Keywords:

ISOMERASE

Title:

The R90C clinical variant of human bisphosphoglycerate mutase (hBPGM).

Biological Source:

Source Organism(s):

Homo sapiens (Taxon ID: 9606)

Expression System(s):

Escherichia coli bl21(de3)

Method Details:

Experimental Method:

X-RAY DIFFRACTION

Resolution:

2.35 Å

R-Value Free:

0.27

R-Value Work:

0.22

R-Value Observed:

0.23

Space Group:

P 1

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Macromolecular Entities

Structures with similar UniProt ID

Protein Blast

Polymer Type:polypeptide(L)
Molecule:Bisphosphoglycerate mutase
Gene (Uniprot):BPGM
Chain IDs:A, B, C, D
Chain Length:267
Number of Molecules:4
Biological Source:Homo sapiens

UniProt ID:P07738 Pfam ID:PF00300 EC:5.4.2.4

Ligand Molecules

EDO

GOL

Primary Citation

New human bisphosphoglycerate mutase structures provide insights into the structural basis of BPGM deficiency and citrate inhibition.

Martinez-Rodriguez, S, Torres, J.M, Sanchez, P, Ortega, E, Gavira, J.A.Show

Int. J. Biol. Macromol. 338 149491 149491 (2026)

PMID: 41354380 DOI: 10.1016/j.ijbiomac.2025.149491

Primary Citation of related structures

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