9RUZ image
Deposition Date 2025-07-06
Release Date 2026-07-15
Last Version Date 2026-07-15
Entry Detail
PDB ID:
9RUZ
Keywords:
LYASE
Title:
Crystal structure of human carbonic anhydrase II in complex with the inhibitor Aprocitentan
Biological Source:
Source Organism(s):
Homo sapiens (Taxon ID: 9606)
Expression System(s):
Escherichia coli
Method Details:
Experimental Method:
X-RAY DIFFRACTION
Resolution:
1.65 Å
R-Value Free:
0.32
R-Value Work:
0.28
R-Value Observed:
0.28
Space Group:
P 1 21 1
9RUZ validation report missing
Macromolecular Entities
Structures with similar UniProt ID
Structural Superimposition Protein Blast
Polymer Type:polypeptide(L)
Molecule:Carbonic anhydrase 2
Gene (Uniprot):CA2
Chain IDs:A
Chain Length:260
Number of Molecules:1
Biological Source:Homo sapiens
UniProt ID:P00918 Pfam ID:PF00194 EC:4.2.1.1
Ligand Molecules
A1JJR
GOL
ZN
Primary Citation
Crystal structure of human carbonic anhydrase II in complex with the inhibitor Aprocitentan
To Be Published ? ? ? (?)
Primary Citation of related structures
9RUZ
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