ISDA: 9RIG

Deposition Date 2025-06-11

Release Date 2026-04-29

Last Version Date 2026-04-29

Entry Detail

PDB ID:

9RIG

Keywords:

VIRUS

Title:

EV-A71 (genotype B2) in complex with 16-2-9D Fab

Biological Source:

Source Organism(s):

Homo sapiens (Taxon ID: 9606)
Chlorocebus aethiops (Taxon ID: 9534)

Expression System(s):

Homo sapiens

Method Details:

Experimental Method:

ELECTRON MICROSCOPY

Resolution:

3.70 Å

Aggregation State:

PARTICLE

Reconstruction Method:

SINGLE PARTICLE

Download Validation Report

Macromolecular Entities

Structures with similar UniProt ID

Protein Blast

Polymer Type:polypeptide(L)
Molecule:Genome polyprotein
Chain IDs:A
Chain Length:297
Number of Molecules:1
Biological Source:Chlorocebus aethiops

UniProt ID:A0A2L1GIK5

Structures with similar UniProt ID

Protein Blast

Polymer Type:polypeptide(L)
Molecule:Genome polyprotein
Chain IDs:B
Chain Length:245
Number of Molecules:1
Biological Source:Chlorocebus aethiops

UniProt ID:E5RPG5

Structures with similar UniProt ID

Protein Blast

Polymer Type:polypeptide(L)
Molecule:Genome polyprotein
Chain IDs:C
Chain Length:242
Number of Molecules:1
Biological Source:Chlorocebus aethiops

UniProt ID:A0A0E3SXU7

Structures with similar UniProt ID

Protein Blast

Polymer Type:polypeptide(L)
Molecule:Capsid protein
Chain IDs:F (auth: D)
Chain Length:69
Number of Molecules:1
Biological Source:Chlorocebus aethiops

UniProt ID:A8TPY9

Structures with similar UniProt ID

Protein Blast

Polymer Type:polypeptide(L)
Molecule:16-2-9D heavy chain
Chain IDs:D (auth: H)
Chain Length:239
Number of Molecules:1
Biological Source:Homo sapiens

UniProt ID:9RIG

Structures with similar UniProt ID

Protein Blast

Polymer Type:polypeptide(L)
Molecule:16-2-9D light chain
Chain IDs:E (auth: L)
Chain Length:216
Number of Molecules:1
Biological Source:Homo sapiens

UniProt ID:9RIG

Ligand Molecules

SPH

Primary Citation

Structural and functional mapping of protective human monoclonal antibodies against enterovirus A71

Zhou, D, Kotecha, A, Kelly, J.T, Huang, P, Chen, Y, Walter, T.S, Duyvesteyn, H.M.E, Owens, R.J, Ho, S, Lin, T, Fry, E.E, Ren, J, Huang, K, Stuart, D.I.Show

Science Advances ? ? ? (2026)

Primary Citation of related structures

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