ISDA: 9RHH

Deposition Date 2025-06-09

Release Date 2026-07-15

Last Version Date 2026-07-15

Entry Detail

PDB ID:

9RHH

Keywords:

TRANSFERASE

Title:

Crystal structure of Kinase domain of HRI kinase

Biological Source:

Source Organism(s):

Homo sapiens (Taxon ID: 9606)

Expression System(s):

Escherichia coli k-12

Method Details:

Experimental Method:

X-RAY DIFFRACTION

Resolution:

2.08 Å

R-Value Free:

0.23

R-Value Work:

0.20

R-Value Observed:

0.20

Space Group:

P 1 21 1

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Macromolecular Entities

Structures with similar UniProt ID

Structural Superimposition Protein Blast

Polymer Type:polypeptide(L)
Molecule:Eukaryotic translation initia
Chain IDs:A, B
Chain Length:310
Number of Molecules:2
Biological Source:Homo sapiens

UniProt ID:Q9BQI3 Pfam ID:PF00069 EC:2.7.11.1

Modified Residue

Compound ID	Chain ID	Parent Comp ID	Details	2D Image
SEP	A	SER	modified residue

Ligand Molecules

GOL

PEG

Primary Citation

Structure-function studies of HRIKD-deltaKI, a Minimal Kinase Domain of Human Heme-Regulated Inhibitor Kinase

Rajasekaran, M.B, Booth, J, Crepin, D.F, Roe, S.M, Zhou, L, Gianga, T.M, Siligardi, G, Gonzalez-Mendez, R, Staikopoulou, M, Hassan, H, Oliver, A, Mancini, E, Spencer, J.Show

Biorxiv ? ? ? (2026)

DOI: 10.64898/2026.07.06.735516

Primary Citation of related structures

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