ISDA: 9RGO

Deposition Date 2025-06-06

Release Date 2026-03-18

Last Version Date 2026-03-25

Entry Detail

PDB ID:

9RGO

Keywords:

MEMBRANE PROTEIN

Title:

SsCl at pH 9 - Desensitized

Biological Source:

Source Organism(s):

Sarcoptes scabiei (Taxon ID: 52283)

Expression System(s):

Spodoptera frugiperda

Method Details:

Experimental Method:

ELECTRON MICROSCOPY

Resolution:

3.14 Å

Aggregation State:

PARTICLE

Reconstruction Method:

SINGLE PARTICLE

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Macromolecular Entities

Polymer Type:polypeptide(L)
Molecule:pH gated chloride channel
Chain IDs:A, B, C, D, E
Chain Length:293
Number of Molecules:5
Biological Source:Sarcoptes scabiei

Ligand Molecules

Primary Citation

Structure of a pH-sensitive pentameric ligand-gated ion channel from the Sarcoptes scabies mite.

Kleiz-Ferreira, J, Brams, M, Harrison, P.J, Gallagher, C.I, Nys, M, Donze, Y, Quigley, A, Bertrand, D, Ulens, C.Show

Nat Commun ? ? ? (2026)

PMID: 41820392 DOI: 10.1038/s41467-026-70575-0

Primary Citation of related structures

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