ISDA: 9R83

Deposition Date 2025-05-15

Release Date 2026-07-08

Last Version Date 2026-07-08

Entry Detail

PDB ID:

9R83

Keywords:

TRANSFERASE

Title:

KOD-H4 DNA polymerase mutant in a ternary complex with HNA:DNA containing six HNA nucleotides and a 2',3'-dideoxycytidine at the 3'-end of the DNA primer complexed to a natural dATP in the active site

Biological Source:

Source Organism(s):

Thermococcus kodakarensis KOD1 (Taxon ID: 69014)
synthetic construct (Taxon ID: 32630)

Expression System(s):

Escherichia coli

Method Details:

Experimental Method:

X-RAY DIFFRACTION

Resolution:

2.80 Å

R-Value Free:

0.25

R-Value Work:

0.21

R-Value Observed:

0.21

Space Group:

P 21 21 21

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Macromolecular Entities

Structures with similar UniProt ID

Protein Blast

Polymer Type:polypeptide(L)
Molecule:DNA polymerase
Chain IDs:B (auth: A), C (auth: B)
Chain Length:774
Number of Molecules:2
Biological Source:Thermococcus kodakarensis KOD1

UniProt ID:D0VWU9 EC:2.7.7.7

Polymer Type:polydeoxyribonucleotide
Molecule:DNA (5'-D(P*(6HA)P*(6HC)P*(6H
Chain IDs:E (auth: D), F (auth: E)
Chain Length:16
Number of Molecules:2
Biological Source:synthetic construct

Polymer Type:polydeoxyribonucleotide
Molecule:DNA (5'-D(*GP*AP*CP*CP*AP*CP*
Chain IDs:A (auth: F), D (auth: C)
Chain Length:12
Number of Molecules:2
Biological Source:synthetic construct

Ligand Molecules