ISDA: 9R6T

Deposition Date 2025-05-13

Release Date 2026-03-11

Last Version Date 2026-04-01

Entry Detail

PDB ID:

9R6T

Keywords:

VIRAL PROTEIN

Title:

Prefusion stabilized spike glycoprotein of equine coronavirus.

Biological Source:

Source Organism(s):

Equine coronavirus (Taxon ID: 136187)

Expression System(s):

Homo sapiens

Method Details:

Experimental Method:

ELECTRON MICROSCOPY

Resolution:

2.76 Å

Aggregation State:

PARTICLE

Reconstruction Method:

SINGLE PARTICLE

Download Validation Report

Macromolecular Entities

Polymer Type:polypeptide(L)
Molecule:Spike glycoprotein
Chain IDs:A, B, C
Chain Length:1302
Number of Molecules:3
Biological Source:Equine coronavirus

Ligand Molecules

8Z9

NAG

Primary Citation

AI-guided prefusion stabilization of the human coronavirus OC43 spike protein enables universal embecovirus antigen design.

Melchers, J.M, Juraszek, J, Hulswit, R.J.G, van Overveld, D, Le, L, van Kuppeveld, F.J.M, Hurdiss, D.L, Bosch, B.J, Langedijk, J.P.M, Bakkers, M.J.G.Show

Plos Pathog. 22 e1013998 e1013998 (2026)

PMID: 41871159 DOI: 10.1371/journal.ppat.1013998

Primary Citation of related structures

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