9R3S image
Deposition Date 2025-05-06
Release Date 2026-07-22
Last Version Date 2026-07-22
Entry Detail
PDB ID:
9R3S
Keywords:
SIGNALING PROTEIN
Title:
pro-TGF-beta1 in complex with the third TB Domain from Latent Transforming Growth Factor-beta Binding Protein-1
Biological Source:
Source Organism(s):
Homo sapiens (Taxon ID: 9606)
Expression System(s):
Homo sapiens
Method Details:
Experimental Method:
ELECTRON MICROSCOPY
Resolution:
3.06 Å
Aggregation State:
PARTICLE
Reconstruction Method:
SINGLE PARTICLE
9R3S validation report missing
Macromolecular Entities
Structures with similar UniProt ID
Structural Superimposition Protein Blast
Polymer Type:polypeptide(L)
Molecule:Transforming growth factor be
Gene (Uniprot):TGFB1
Chain IDs:A (auth: B), B (auth: A)
Chain Length:369
Number of Molecules:2
Biological Source:Homo sapiens
UniProt ID:P01137 Pfam ID:PF00688, PF00019
Structures with similar UniProt ID
Structural Superimposition Protein Blast
Polymer Type:polypeptide(L)
Molecule:Latent-transforming growth fa
Gene (Uniprot):LTBP1
Chain IDs:C
Chain Length:435
Number of Molecules:1
Biological Source:Homo sapiens
UniProt ID:Q14766 Pfam ID:PF00683, PF07645
Ligand Molecules
NAG
Primary Citation
Structural basis for the contribution of latent TGF beta binding protein to TGF beta latency and activation
Nat Commun ? ? ? (2026)
Primary Citation of related structures
5VQP
1KSQ
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