9QVX image
Deposition Date 2025-04-13
Release Date 2026-04-22
Last Version Date 2026-04-22
Entry Detail
PDB ID:
9QVX
Keywords:
HYDROLASE
Title:
The targeting of non-fibrillar polyQ via distinct VCP-proteasome coupling
Biological Source:
Source Organism(s):
Homo sapiens (Taxon ID: 9606)
Expression System(s):
Homo sapiens
Method Details:
Experimental Method:
ELECTRON MICROSCOPY
Resolution:
3.90 Å
Aggregation State:
PARTICLE
Reconstruction Method:
SINGLE PARTICLE
9QVX validation report missing
Macromolecular Entities
Structures with similar UniProt ID
Protein Blast
Polymer Type:polypeptide(L)
Molecule:Proteasome subunit alpha type
Gene (Uniprot):PSMA6
Chain IDs:A, O
Chain Length:240
Number of Molecules:2
Biological Source:Homo sapiens
UniProt ID:P60900 Pfam ID:PF10584, PF00227
Structures with similar UniProt ID
Protein Blast
Polymer Type:polypeptide(L)
Molecule:Proteasome subunit alpha type
Gene (Uniprot):PSMA2
Chain IDs:B, P
Chain Length:229
Number of Molecules:2
Biological Source:Homo sapiens
UniProt ID:P25787 Pfam ID:PF10584, PF00227
Structures with similar UniProt ID
Protein Blast
Polymer Type:polypeptide(L)
Molecule:Proteasome subunit alpha type
Gene (Uniprot):PSMA4
Chain IDs:C, Q
Chain Length:247
Number of Molecules:2
Biological Source:Homo sapiens
UniProt ID:P25789 Pfam ID:PF10584, PF00227 EC:3.4.25.1
Structures with similar UniProt ID
Protein Blast
Polymer Type:polypeptide(L)
Molecule:Proteasome subunit alpha type
Gene (Uniprot):PSMA7
Chain IDs:D, R
Chain Length:4
Number of Molecules:2
Biological Source:Homo sapiens
UniProt ID:O14818 Pfam ID:PF10584, PF00227
Structures with similar UniProt ID
Protein Blast
Polymer Type:polypeptide(L)
Molecule:Proteasome subunit alpha type
Gene (Uniprot):PSMA5
Chain IDs:E, S
Chain Length:233
Number of Molecules:2
Biological Source:Homo sapiens
UniProt ID:P28066 Pfam ID:PF10584, PF00227 EC:3.4.25.1
Structures with similar UniProt ID
Protein Blast
Polymer Type:polypeptide(L)
Molecule:Proteasome subunit alpha type
Gene (Uniprot):PSMA1
Chain IDs:F, T
Chain Length:233
Number of Molecules:2
Biological Source:Homo sapiens
UniProt ID:P25786 Pfam ID:PF10584, PF00227
Structures with similar UniProt ID
Protein Blast
Polymer Type:polypeptide(L)
Molecule:Proteasome subunit alpha type
Gene (Uniprot):PSMA3
Chain IDs:G, U
Chain Length:239
Number of Molecules:2
Biological Source:Homo sapiens
UniProt ID:P25788 Pfam ID:PF10584, PF00227
Structures with similar UniProt ID
Protein Blast
Polymer Type:polypeptide(L)
Molecule:Proteasome subunit beta type-
Gene (Uniprot):PSMB6
Chain IDs:H, V
Chain Length:202
Number of Molecules:2
Biological Source:Homo sapiens
UniProt ID:P28072 Pfam ID:PF00227 EC:3.4.25.1
Structures with similar UniProt ID
Protein Blast
Polymer Type:polypeptide(L)
Molecule:Proteasome subunit beta type-
Gene (Uniprot):PSMB7
Chain IDs:I, W
Chain Length:220
Number of Molecules:2
Biological Source:Homo sapiens
UniProt ID:Q99436 Pfam ID:PF00227, PF12465 EC:3.4.25.1
Structures with similar UniProt ID
Protein Blast
Polymer Type:polypeptide(L)
Molecule:Proteasome subunit beta type-
Gene (Uniprot):PSMB3
Chain IDs:J, X
Chain Length:204
Number of Molecules:2
Biological Source:Homo sapiens
UniProt ID:P49720 Pfam ID:PF00227 EC:3.4.25.1
Structures with similar UniProt ID
Protein Blast
Polymer Type:polypeptide(L)
Molecule:Proteasome subunit beta type-
Gene (Uniprot):PSMB2
Chain IDs:K, Y
Chain Length:196
Number of Molecules:2
Biological Source:Homo sapiens
UniProt ID:P49721 Pfam ID:PF00227 EC:3.4.25.1
Structures with similar UniProt ID
Protein Blast
Polymer Type:polypeptide(L)
Molecule:Proteasome subunit beta type-
Gene (Uniprot):PSMB5
Chain IDs:L, Z
Chain Length:200
Number of Molecules:2
Biological Source:Homo sapiens
UniProt ID:P28074 Pfam ID:PF00227 EC:3.4.25.1
Structures with similar UniProt ID
Protein Blast
Polymer Type:polypeptide(L)
Molecule:Proteasome subunit beta type-
Gene (Uniprot):PSMB1
Chain IDs:M, AA (auth: a)
Chain Length:240
Number of Molecules:2
Biological Source:Homo sapiens
UniProt ID:P20618 Pfam ID:PF00227
Structures with similar UniProt ID
Protein Blast
Polymer Type:polypeptide(L)
Molecule:Proteasome subunit beta type-
Gene (Uniprot):PSMB4
Chain IDs:N, BA (auth: b)
Chain Length:229
Number of Molecules:2
Biological Source:Homo sapiens
UniProt ID:P28070 Pfam ID:PF00227
Structures with similar UniProt ID
Protein Blast
Polymer Type:polypeptide(L)
Molecule:polypeptide traced as poly-Al
Chain IDs:CA (auth: c), DA (auth: d)
Chain Length:247
Number of Molecules:2
Biological Source:Homo sapiens
UniProt ID:9QVX
Ligand Molecules
NA
Primary Citation
The targeting of non-fibrillar polyQ via distinct VCP-proteasome coupling
To be published ? ? ? (?)
Primary Citation of related structures
9QVX
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