ISDA: 9QM9

Deposition Date 2025-03-22

Release Date 2025-08-20

Last Version Date 2026-03-04

Entry Detail

PDB ID:

9QM9

Keywords:

MEMBRANE PROTEIN

Title:

TMEM55B tandem RING-like domains in complex with RILPL1 C-terminal peptide

Biological Source:

Source Organism(s):

Homo sapiens (Taxon ID: 9606)

Expression System(s):

Escherichia coli bl21(de3), Synthetic construct

Method Details:

Experimental Method:

X-RAY DIFFRACTION

Resolution:

1.55 Å

R-Value Free:

0.24

R-Value Work:

0.20

R-Value Observed:

0.20

Space Group:

P 21 21 21

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Macromolecular Entities

Structures with similar UniProt ID

Protein Blast

Polymer Type:polypeptide(L)
Molecule:Type 1 phosphatidylinositol 4
Gene (Uniprot):PIP4P1
Mutagens:C136S, C140A
Chain IDs:A, B
Chain Length:91
Number of Molecules:2
Biological Source:Homo sapiens

UniProt ID:Q86T03 Pfam ID:PF09788 EC:3.1.3.78

Structures with similar UniProt ID

Protein Blast

Polymer Type:polypeptide(L)
Molecule:RILP-like protein 1
Gene (Uniprot):RILPL1
Chain IDs:C (auth: D)
Chain Length:13
Number of Molecules:1
Biological Source:Homo sapiens

UniProt ID:Q5EBL4

Ligand Molecules

Primary Citation

Structural basis for binding of RILPL1 to TMEM55B reveals a lysosomal platform for adaptor assembly through a conserved peptide motif.

Waschbusch, D, Pal, P, Nirujogi, R.S, Cavin, M, Singh, J, Alessi, D.R, Khan, A.R.Show

Structure 34 296 310.e5 (2026)

PMID: 41314214 DOI: 10.1016/j.str.2025.11.003

Primary Citation of related structures

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