ISDA: 8OQH

Deposition Date 2023-04-12

Release Date 2023-11-29

Last Version Date 2026-03-04

Entry Detail

PDB ID:

8OQH

Keywords:

MEMBRANE PROTEIN

Title:

Structure of the cytosolic domain of lysosome-associated TMEM55B

Biological Source:

Source Organism(s):

Homo sapiens (Taxon ID: 9606)

Expression System(s):

Escherichia coli

Method Details:

Experimental Method:

X-RAY DIFFRACTION

Resolution:

1.76 Å

R-Value Free:

0.22

R-Value Work:

0.19

R-Value Observed:

0.19

Space Group:

P 1 21 1

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Macromolecular Entities

Structures with similar UniProt ID

Protein Blast

Polymer Type:polypeptide(L)
Molecule:Type 1 phosphatidylinositol 4
Gene (Uniprot):PIP4P1
Chain IDs:A, B
Chain Length:91
Number of Molecules:2
Biological Source:Homo sapiens

UniProt ID:Q86T03 Pfam ID:PF09788 EC:3.1.3.78

Ligand Molecules

Primary Citation

Structural basis for binding of RILPL1 to TMEM55B reveals a lysosomal platform for adaptor assembly through a conserved peptide motif.

Waschbusch, D, Pal, P, Nirujogi, R.S, Cavin, M, Singh, J, Alessi, D.R, Khan, A.R.Show

Structure 34 296 310.e5 (2026)

PMID: 41314214 DOI: 10.1016/j.str.2025.11.003

Primary Citation of related structures

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