ISDA: 9QIE

Deposition Date 2025-03-17

Release Date 2026-09-30

Last Version Date 2026-09-30

Entry Detail

PDB ID:

9QIE

Keywords:

HYDROLASE

Title:

Crystal Structure of human MLH1 N-terminal domain I219V with AMP-PNP

Biological Source:

Source Organism(s):

Homo sapiens (Taxon ID: 9606)

Expression System(s):

Escherichia coli bl21(de3)

Method Details:

Experimental Method:

X-RAY DIFFRACTION

Resolution:

2.15 Å

R-Value Free:

0.24

R-Value Work:

0.21

Space Group:

P 1 21 1

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Macromolecular Entities

Structures with similar UniProt ID

Structural Superimposition Protein Blast

Polymer Type:polypeptide(L)
Molecule:DNA mismatch repair protein M
Gene (Uniprot):MLH1
Mutagens:I219V
Chain IDs:A, B, C, D
Chain Length:0
Number of Molecules:4
Biological Source:Homo sapiens

UniProt ID:P40692 Pfam ID:PF13589, PF01119

Ligand Molecules

ACT

ANP

EDO

GOL

MES

Primary Citation

Crystal Structure of human MLH1 N-terminal domain I219V with AMP-PNP

Bandera, A.M, Thomsen, M.Show

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