ISDA: 9Q7P

Deposition Date 2025-08-25

Release Date 2026-08-05

Last Version Date 2026-08-05

Entry Detail

PDB ID:

9Q7P

Keywords:

METAL BINDING PROTEIN

Title:

Solution Structure of the Beta Domain of Human MT1A Bound to 6 Cu(I) Ions

Biological Source:

Source Organism(s):

Homo sapiens (Taxon ID: 9606)

Expression System(s):

Escherichia coli bl21(de3)

Method Details:

Experimental Method:

SOLUTION NMR

Conformers Calculated:

Conformers Submitted:

Selection Criteria:

structures with the lowest energy

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Macromolecular Entities

Structures with similar UniProt ID

Structural Superimposition Protein Blast

Polymer Type:polypeptide(L)
Molecule:Immunoglobulin G-binding prot
Gene (Uniprot):MT1A
Chain IDs:A
Chain Length:90
Number of Molecules:1
Biological Source:Homo sapiens

UniProt ID:P04731 Pfam ID:PF00131

Ligand Molecules

CU1

Primary Citation

The NMR structure of human Cu6-B MT1 reveals that the Cu6S9 binding site adopts a ladder structure not the closed prism structure of inorganic Cu(I)-thiolate compounds

Melenbacher, A, Rintala-Dempsey, A.C, Liu, L, Chang, L, Shaw, G.S, Stillman, M.J.Show

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