ISDA: 9PXQ

Deposition Date 2025-08-06

Release Date 2026-09-02

Last Version Date 2026-09-30

Entry Detail

PDB ID:

9PXQ

Keywords:

OXIDOREDUCTASE

Title:

Crystal structure of bovine ALDH3A1 in complex with Canonical Redox Cofactors, NAD+

Biological Source:

Source Organism(s):

Bos taurus (Taxon ID: 9913)

Expression System(s):

Escherichia coli

Method Details:

Experimental Method:

X-RAY DIFFRACTION

Resolution:

1.46 Å

R-Value Free:

0.19

R-Value Work:

0.17

R-Value Observed:

0.17

Space Group:

P 1

Download Validation Report

Macromolecular Entities

Structures with similar UniProt ID

Structural Superimposition Protein Blast

Polymer Type:polypeptide(L)
Molecule:Aldehyde dehydrogenase
Gene (Uniprot):ALDH3A1
Chain IDs:A, B
Chain Length:452
Number of Molecules:2
Biological Source:Bos taurus

UniProt ID:F1N015 Pfam ID:PF00171

Ligand Molecules

GOL

NAD

Primary Citation

A sequence motif enables widespread use of noncanonical redox cofactors in natural enzymes.

Saleh, S, Hsu, N.H, Luu, E, Martin, V.C, Ng, H.J.C, Black, W.B, Zhang, S, Kim, J.K, Sankaran, B, Tran, A.H.T, Hayes, R.L, Siegel, J.B, Qiao, F, Li, H.Show

Nat.Chem.Biol. ? ? ? (2026)

PMID: 42717052 DOI: 10.1038/s41589-026-02315-w

Primary Citation of related structures

Feedback Form