ISDA: 9PXI

Deposition Date 2025-08-05

Release Date 2026-06-10

Last Version Date 2026-06-10

Entry Detail

PDB ID:

9PXI

Keywords:

MEMBRANE PROTEIN

Title:

Cryo-EM structure of BAM from P. aeruginosa PAO1 in complex with Pyocin L1

Biological Source:

Source Organism(s):

Pseudomonas aeruginosa (Taxon ID: 287)
Pseudomonas aeruginosa PAO1 (Taxon ID: 208964)

Expression System(s):

Escherichia coli bl21(de3)

Method Details:

Experimental Method:

ELECTRON MICROSCOPY

Resolution:

2.85 Å

Aggregation State:

PARTICLE

Reconstruction Method:

SINGLE PARTICLE

Download Validation Report

Macromolecular Entities

Structures with similar UniProt ID

Protein Blast

Polymer Type:polypeptide(L)
Molecule:Outer membrane protein assemb
Gene (Uniprot):opr86
Chain IDs:D (auth: A)
Chain Length:834
Number of Molecules:1
Biological Source:Pseudomonas aeruginosa PAO1

UniProt ID:Q9HXY4 Pfam ID:PF07244, PF01103

Structures with similar UniProt ID

Protein Blast

Polymer Type:polypeptide(L)
Molecule:Outer membrane protein assemb
Gene (Uniprot):bamB
Chain IDs:C (auth: B)
Chain Length:380
Number of Molecules:1
Biological Source:Pseudomonas aeruginosa PAO1

UniProt ID:Q9HXJ7 Pfam ID:PF13360

Structures with similar UniProt ID

Protein Blast

Polymer Type:polypeptide(L)
Molecule:Outer membrane protein assemb
Gene (Uniprot):PA1011
Chain IDs:B (auth: C)
Chain Length:396
Number of Molecules:1
Biological Source:Pseudomonas aeruginosa PAO1

UniProt ID:Q9I4W2 Pfam ID:PF06804

Structures with similar UniProt ID

Protein Blast

Polymer Type:polypeptide(L)
Molecule:Outer membrane protein assemb
Gene (Uniprot):bamD
Chain IDs:A (auth: D)
Chain Length:341
Number of Molecules:1
Biological Source:Pseudomonas aeruginosa PAO1

UniProt ID:P33641 Pfam ID:PF13525

Structures with similar UniProt ID

Protein Blast

Polymer Type:polypeptide(L)
Molecule:Outer membrane protein assemb
Gene (Uniprot):bamE
Chain IDs:E
Chain Length:176
Number of Molecules:1
Biological Source:Pseudomonas aeruginosa PAO1

UniProt ID:O68562 Pfam ID:PF04355

Structures with similar UniProt ID

Protein Blast

Polymer Type:polypeptide(L)
Molecule:Pyocin L1
Gene (Uniprot):pyocin L1
Chain IDs:F
Chain Length:276
Number of Molecules:1
Biological Source:Pseudomonas aeruginosa

UniProt ID:T2LG16

Ligand Molecules

Primary Citation

A potent protein antibiotic kills Pseudomonas aeruginosa by inhibiting the BAM complex

Munder, F, Johnson, M, Samuels, I, McCaughey, L, Zdorevskyi, O, Wang, C, Kropp, A, Price, E.P, Sarovich, D.S, Varshney, S, Venugopal, H, Sharma, V, Doyle, M, Short, F, Ghosal, D, Connolly, J, Knott, G, Grinter, R.Show

To Be Published ? ? ? (?)

Primary Citation of related structures

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