9PTU image
Deposition Date 2025-07-29
Release Date 2026-07-01
Last Version Date 2026-07-01
Entry Detail
PDB ID:
9PTU
Keywords:
LIGASE
Title:
Cryo-EM structure of the DCAF11 E3 ligase bound to the DDX18 helicase mediated by GSH-M12
Biological Source:
Source Organism(s):
Homo sapiens (Taxon ID: 9606)
Expression System(s):
Trichoplusia ni
Method Details:
Experimental Method:
ELECTRON MICROSCOPY
Resolution:
2.38 Å
Aggregation State:
PARTICLE
Reconstruction Method:
SINGLE PARTICLE
9PTU validation report missing
Macromolecular Entities
Structures with similar UniProt ID
Protein Blast
Polymer Type:polypeptide(L)
Molecule:DDB1- and CUL4-associated fac
Gene (Uniprot):DCAF11
Chain IDs:A
Chain Length:590
Number of Molecules:1
Biological Source:Homo sapiens
UniProt ID:Q8TEB1 Pfam ID:PF00400
Structures with similar UniProt ID
Protein Blast
Polymer Type:polypeptide(L)
Molecule:DNA damage-binding protein 1
Gene (Uniprot):DDB1
Chain IDs:C (auth: B)
Chain Length:864
Number of Molecules:1
Biological Source:Homo sapiens
UniProt ID:Q16531 Pfam ID:PF10433, PF03178
Structures with similar UniProt ID
Protein Blast
Polymer Type:polypeptide(L)
Molecule:ATP-dependent RNA helicase DD
Gene (Uniprot):DDX18
Chain IDs:B (auth: C)
Chain Length:478
Number of Molecules:1
Biological Source:Homo sapiens
UniProt ID:Q9NVP1 Pfam ID:PF00270, PF00271, PF13959 EC:3.6.4.13
Ligand Molecules
A1CK5
Primary Citation
Cryo-EM structure of the DCAF11 E3 ligase bound to the DDX18 helicase mediated by GSH-M12
To Be Published ? ? ? (?)
Primary Citation of related structures
9PTU
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