ISDA: 9PSQ

Deposition Date 2025-07-25

Release Date 2026-08-05

Last Version Date 2026-08-05

Entry Detail

PDB ID:

9PSQ

Keywords:

GENE REGULATION

Title:

Co-crystal structure of BAF60A (SMARCD1) bound to PPSC-001

Biological Source:

Source Organism(s):

Homo sapiens (Taxon ID: 9606)

Expression System(s):

Escherichia coli 'bl21-gold(de3)plyss ag'

Method Details:

Experimental Method:

X-RAY DIFFRACTION

Resolution:

2.31 Å

R-Value Free:

0.25

R-Value Work:

0.21

R-Value Observed:

0.21

Space Group:

C 1 2 1

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Macromolecular Entities

Structures with similar UniProt ID

Structural Superimposition Protein Blast

Polymer Type:polypeptide(L)
Molecule:SWI/SNF-related matrix-associ
Gene (Uniprot):SMARCD1
Chain IDs:A
Chain Length:255
Number of Molecules:1
Biological Source:Homo sapiens

UniProt ID:Q96GM5 Pfam ID:PF02201

Ligand Molecules

A1CLC

Primary Citation

Structural and functional basis of PU.1-BAF interaction enables targeting of lineage-specific transcription

Sadalge, D.S, Clasman, J.R, Topal, S, Musser, D, Von der Porten, L, Wu, S, Schultz, S, Austin, W, Huang, D, Setser, J.W, Martinez, M.R, Kiselar, J, Hesler, S, Blevins, S.J, Turegun, B, Palowitch, G.M, Khalil, A, Pulice, J.L, Chance, M.R, Wilson, K.J, Nelen, M, Lahr, D, Sandoval, G.J, Davenport, Y.W, Bellon, S.F, Taherbhoy, A.M.Show

To Be Published ? ? ? (?)

Primary Citation of related structures

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