ISDA: 9PNX

Deposition Date 2025-07-21

Release Date 2026-07-22

Last Version Date 2026-07-22

Entry Detail

PDB ID:

9PNX

Keywords:

IMMUNE SYSTEM

Title:

Crystal structure of anti-IL2Rgamma VH3-20 domain

Biological Source:

Source Organism(s):

Homo sapiens (Taxon ID: 9606)

Expression System(s):

Escherichia coli

Method Details:

Experimental Method:

X-RAY DIFFRACTION

Resolution:

1.35 Å

R-Value Free:

0.20

R-Value Work:

0.18

R-Value Observed:

0.19

Space Group:

P 43

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Macromolecular Entities

Structural Superimposition Protein Blast

Polymer Type:polypeptide(L)
Molecule:anti-IL2Rgamma VH3-20 domain
Chain IDs:A (auth: H)
Chain Length:128
Number of Molecules:1
Biological Source:Homo sapiens

Ligand Molecules

Primary Citation

Computational Design of the Functional Human VH Germline Repertoire to Enable Conditional Multi-Specific Therapeutic Development

Theiker, D, Hanna, J, Hong, G, Walters, P, Capodagli, G, Buetz-Duncan, C, Carnevale, C, Sereno, A, Karow, M, Chaie, F, Lin, A, Pigott, C.R, Kang, J, Gallo, M, Sharma, R, Del Cid, N, Nicely, N.I, Kuhlman, B, Demarest, S.J.Show

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Primary Citation of related structures

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