9PMS image
Deposition Date 2025-07-18
Release Date 2026-07-22
Last Version Date 2026-07-22
Entry Detail
PDB ID:
9PMS
Keywords:
ANTITUMOR PROTEIN
Title:
Epitope editing of CD90 protects hematopoietic stem cells from immunotherapy and enables targeted enrichment for gene therapy
Biological Source:
Source Organism(s):
Mus musculus (Taxon ID: 10090)
Homo sapiens (Taxon ID: 9606)
Expression System(s):
Cricetulus griseus, Homo sapiens
Method Details:
Experimental Method:
ELECTRON MICROSCOPY
Resolution:
3.56 Å
Aggregation State:
PARTICLE
Reconstruction Method:
SINGLE PARTICLE
9PMS validation report missing
Macromolecular Entities
Structural Superimposition Protein Blast
Polymer Type:polypeptide(L)
Molecule:Antibody heavy chain
Chain IDs:A
Chain Length:220
Number of Molecules:1
Biological Source:Mus musculus
Structural Superimposition Protein Blast
Polymer Type:polypeptide(L)
Molecule:Antibody light chain
Chain IDs:B
Chain Length:214
Number of Molecules:1
Biological Source:Mus musculus
Structures with similar UniProt ID
Structural Superimposition Protein Blast
Polymer Type:polypeptide(L)
Molecule:Thy-1 membrane glycoprotein
Gene (Uniprot):THY1
Chain IDs:C
Chain Length:113
Number of Molecules:1
Biological Source:Homo sapiens
UniProt ID:P04216 Pfam ID:PF00047
Structural Superimposition Protein Blast
Polymer Type:polypeptide(L)
Molecule:Antibody heavy chain
Chain IDs:D (auth: H)
Chain Length:218
Number of Molecules:1
Biological Source:Mus musculus
Structural Superimposition Protein Blast
Polymer Type:polypeptide(L)
Molecule:Antibody light chain
Chain IDs:E (auth: L)
Chain Length:214
Number of Molecules:1
Biological Source:Mus musculus
Ligand Molecules
NAG
Primary Citation
Epitope editing of CD90 protects hematopoietic stem cells from immunotherapy and enables targeted enrichment for gene therapy
To Be Published ? ? ? (?)
Primary Citation of related structures
9PMS
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