9P9M image
Deposition Date 2025-06-24
Release Date 2026-04-29
Last Version Date 2026-04-29
Entry Detail
PDB ID:
9P9M
Keywords:
VIRUS LIKE PARTICLE
Title:
CA-SP1 immature lattice assembled in vitro with inhibitor lenacapavir (dialyzed to 50nM)
Biological Source:
Source Organism(s):
Human immunodeficiency virus type 1 (NEW YORK-5 ISOLATE) (Taxon ID: 11698)
Expression System(s):
Escherichia coli bl21(de3)
Method Details:
Experimental Method:
ELECTRON MICROSCOPY
Resolution:
2.93 Å
Aggregation State:
PARTICLE
Reconstruction Method:
SINGLE PARTICLE
9P9M validation report missing
Macromolecular Entities
Structures with similar UniProt ID
Protein Blast
Polymer Type:polypeptide(L)
Molecule:Gag polyprotein
Gene (Uniprot):gag
Chain IDs:A, B, C, D, E, F, G, H, I, J, K, L, M, N, O, P, Q, R
Chain Length:229
Number of Molecules:18
Biological Source:Human immunodeficiency virus type 1 (NEW YORK-5 ISOLATE)
UniProt ID:P12493
Ligand Molecules
IHP
QNG
Primary Citation
Distinct Target Site of Lenacapavir in Immature HIV-1 and Concurrent Binding with the Maturation Inhibitor Bevirimat.
J.Am.Chem.Soc. 147 42685 42700 (2025)
PMID: 41198571 DOI: 10.1021/jacs.5c13735
Primary Citation of related structures
9P9M
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