9P8A image
Deposition Date 2025-06-22
Release Date 2026-03-25
Last Version Date 2026-03-25
Entry Detail
PDB ID:
9P8A
Keywords:
SIGNALING PROTEIN
Title:
NTSR1-G11-NTS(8-13) GTP-Bound Complex in the Canonical, AHD Closed State 3DVA Separated 2 (C-Closed*-GTP)
Biological Source:
Source Organism(s):
Homo sapiens (Taxon ID: 9606)
Expression System(s):
Trichoplusia ni
Method Details:
Experimental Method:
ELECTRON MICROSCOPY
Resolution:
3.70 Å
Aggregation State:
PARTICLE
Reconstruction Method:
SINGLE PARTICLE
9P8A validation report
Macromolecular Entities
Structures with similar UniProt ID
Protein Blast
Polymer Type:polypeptide(L)
Molecule:Guanine nucleotide-binding pr
Gene (Uniprot):GNA11
Chain IDs:A
Chain Length:359
Number of Molecules:1
Biological Source:Homo sapiens
UniProt ID:P29992 Pfam ID:PF00503
Structures with similar UniProt ID
Protein Blast
Polymer Type:polypeptide(L)
Molecule:Guanine nucleotide-binding pr
Gene (Uniprot):GNB1
Chain IDs:B
Chain Length:344
Number of Molecules:1
Biological Source:Homo sapiens
UniProt ID:P62873 Pfam ID:PF25391
Structures with similar UniProt ID
Protein Blast
Polymer Type:polypeptide(L)
Molecule:Guanine nucleotide-binding pr
Gene (Uniprot):GNG2
Chain IDs:C (auth: G)
Chain Length:71
Number of Molecules:1
Biological Source:Homo sapiens
UniProt ID:P59768 Pfam ID:PF00631
Ligand Molecules
GTP
Primary Citation
Snapshots of the dynamic basis of NTSR1 G protein subtype promiscuity.
Nature ? ? ? (2026)
PMID: 41813894 DOI: 10.1038/s41586-026-10120-7
Primary Citation of related structures
9P8A
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