9OXB image
Deposition Date 2025-06-03
Release Date 2026-04-22
Last Version Date 2026-04-22
Entry Detail
PDB ID:
9OXB
Title:
CryoEM structure of Ggust-coupled TAS2R43 with aristolochic acid I
Biological Source:
Source Organism(s):
Homo sapiens (Taxon ID: 9606)
Expression System(s):
Method Details:
Experimental Method:
Resolution:
3.00 Å
Aggregation State:
PARTICLE
Reconstruction Method:
SINGLE PARTICLE
Macromolecular Entities
Structures with similar UniProt ID
Protein Blast
Polymer Type:polypeptide(L)
Molecule:Guanine nucleotide-binding pr
Gene (Uniprot):GNAT3
Chain IDs:A
Chain Length:354
Number of Molecules:1
Biological Source:Homo sapiens
Structures with similar UniProt ID
Protein Blast
Polymer Type:polypeptide(L)
Molecule:Guanine nucleotide-binding pr
Gene (Uniprot):GNB1
Chain IDs:B
Chain Length:402
Number of Molecules:1
Biological Source:Homo sapiens
Structures with similar UniProt ID
Protein Blast
Polymer Type:polypeptide(L)
Molecule:Guanine nucleotide-binding pr
Gene (Uniprot):GNG2
Chain IDs:C
Chain Length:71
Number of Molecules:1
Biological Source:Homo sapiens
Structures with similar UniProt ID
Protein Blast
Polymer Type:polypeptide(L)
Molecule:scFv16
Chain IDs:D
Chain Length:267
Number of Molecules:1
Biological Source:Homo sapiens
Structures with similar UniProt ID
Protein Blast
Polymer Type:polypeptide(L)
Molecule:Taste receptor type 2 member
Gene (Uniprot):TAS2R43
Chain IDs:E (auth: R)
Chain Length:645
Number of Molecules:1
Biological Source:Homo sapiens
Ligand Molecules
Primary Citation
Structural insights into coffee bitter taste perception by TAS2R43 receptor
Nat. Struct. Mol. Biol. ? ? ? (2026)
DOI: 10.1038/s41594-026-01776-w
Primary Citation of related structures
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